Program

97
61
10
2
2

Journal Year Published

3
5
18
12
19
9
15
13
13
7
3
10
7
4
2

Author

140
202
181
149
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

73
51
39
16
7
5
4
3
1
1

Keyword

59
33
24
22
19
16
15
14
12
12
11
11
10
9
9
9
9
8
8
8

Journal

13
9
5
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2

NCATS Publications

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.


Hoskins JW, Ofori LO, Chen C, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan J, Zheng W, Austin C, Disney MD, Miller BL, Thornton CA


Nucleic Acids Res. , (42), 6591-602, 2014.

Article Pubmed

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Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.


Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer-Alegre M, Titus S, Zheng W, Sibley DR, Marugan J


J. Med. Chem. , (57), 3450-63, 2014.

Article Pubmed

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Structural basis for inactivation of Giardia lamblia carbamate kinase by disulfiram.


Galkin A, Kulakova L, Lim K, Chen C, Zheng W, Turko IV, Herzberg O


J. Biol. Chem. , (289), 10502-9, 2014.

Article Pubmed

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Chemical signatures and new drug targets for gametocytocidal drug development.


Sun W, Tanaka TQ, Magle CT, Huang W, Southall N, Huang R, Dehdashti SJ, McKew JC, Williamson KC, Zheng W


Sci Rep , (4), 3743, 2014.

Article Pubmed

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Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.


Ottinger E, Kao ML, Carrillo-Carrasco N, Yanjanin N, Shankar RK, Janssen M, Brewster M, Scott I, Xu X, Cradock J, Terse P, Dehdashti SJ, Marugan J, Zheng W, Portilla Weingarten L, Hubbs A, Pavan WJ, Heiss J, Vite CH, Walkley SU, Ory DS, Silber SA, Porter FD, Austin C, McKew JC


Curr Top Med Chem , (14), 330-9, 2014.

Pubmed

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High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.


Ketley A, Chen C, Li X, Arya S, Robinson TE, Granados-Riveron J, Udosen I, Morris GE, Holt I, Furling D, Chaouch S, Haworth B, Southall N, Shinn P, Zheng W, Austin C, Hayes CJ, Brook JD


Hum. Mol. Genet. , (23), 1551-62, 2014.

Article Pubmed

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Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor.


Patnaik S, Marugan J, Liu K, Zheng W, Southall N, Dehdashti SJ, Thorsell A, Heilig M, Bell L, Zook M, Eskay B, Brimacombe K, Austin C


J. Med. Chem. , (56), 9045-56, 2013.

Article Pubmed

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