Program

99
92
5
3
2
1
1

Journal Year Published

3
12
16
11
20
10
8
9
10
12
12
10
12
4

Author

149
202
181
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
43
32
19
18
16
15
15
14
13
13
12
12
12
11
11
10
10
10
9

Journal

16
13
12
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2

NCATS Publications

Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma.


Ju W, Zhang M, Wilson K, Petrus MN, Bamford RN, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (113), 1624-9, 2016.

Article Pubmed

Sample image from publication page

Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1.


Ali-Rahmani F, FitzGerald DJ, Martin S, Patel P, Prunotto M, Ormanoglu P, Thomas C, Pastan I


Cancer Res. , (76), 1560-8, 2016.

Article Pubmed

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.


Doyle JJ, Doyle AJ, Wilson NK, Habashi JP, Bedja D, Whitworth RE, Lindsay ME, Schoenhoff F, Myers L, Huso N, Bachir S, Squires O, Rusholme B, Ehsan H, Huso D, Thomas C, Caulfield MJ, Van Eyk JE, Judge DP, Dietz HC, GenTAC Registry Consortium , MIBAVA Leducq Consortium


Elife , (4), 2015.

Article Pubmed

Sample image from publication page

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.


Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Mathews Griner LA, Ferrer-Alegre M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, Wen X, Zhang S, Shern JF, Yohe ME, Taschner-Mandl S, Shohet JM, Thomas C, Martin SE, Ambros PF, Khan J


Oncotarget , (6), 35247-62, 2015.

Article Pubmed

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.


Mott BT, Eastman R, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer-Alegre M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas C


Sci Rep , (5), 13891, 2015.

Article Pubmed

Sample image from publication page

Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.


Zhang M, Mathews Griner LA, Ju W, Duveau D, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer-Alegre M, Conlon KD, Bamford RN, O'Shea JJ, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (112), 12480-5, 2015.

Article Pubmed

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.


Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin C, Simeonov A, Sittampalam S, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas C


PLoS ONE , (10), e0130796, 2015.

Article Pubmed

Sample image from publication page

A small molecule that inhibits OGT activity in cells.


Ortiz-Meoz RF, Jiang J, Lazarus MB, Orman M, Janetzko J, Fan C, Duveau D, Tan ZW, Thomas C, Walker S


ACS Chem. Biol. , (10), 1392-7, 2015.

Article Pubmed

Sample image from publication page

Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway.


Yin Y, Li X, Sha X, Xi H, Li YF, Shao Y, Mai J, Virtue A, Lopez-Pastrana J, Meng S, Tilley DG, Monroy MA, Choi ET, Thomas C, Jiang X, Wang H, Yang XF


Arterioscler. Thromb. Vasc. Biol. , (35), 804-16, 2015.

Article Pubmed

Sample image from publication page

ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells.


Wang S, Chen XA, Hu J, Jiang J, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y


Mol. Cancer Ther. , (14), 877-88, 2015.

Article Pubmed

Sample image from publication page