Program

92
90
5
3
2
1

Journal Year Published

16
11
20
10
8
9
10
12
12
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12
4

Author

134
182
174
134
125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
41
30
19
18
16
15
15
14
13
13
12
12
11
11
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10
10
9
9

Journal

14
13
11
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2

NCATS Publications

Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.


Onda M, Ghoreschi K, Steward-Tharp S, Thomas C, O'Shea JJ, Pastan IH, FitzGerald DJ


J. Immunol. , (193), 48-55, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.


Jiang J, McCoy JG, Shen M, LeClair C, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas C


Bioorg. Med. Chem. Lett. , (24), 1148-53, 2014.

Article Pubmed

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Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein.


Shukla S, Chufan EE, Singh S, Skoumbourdis AP, Kapoor K, Boxer MB, Duveau D, Thomas C, Talele TT, Ambudkar SV


Leukemia , (28), 961-4, 2014.

Article Pubmed

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CD28 and ITK signals regulate autoreactive T cell trafficking.


Jain N, Miu B, Jiang J, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas C, Sanderson MJ, Berg LJ, Kang J


Nat. Med. , (19), 1632-7, 2013.

Article Pubmed

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Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα.


Chen J, Feigenbaum L, Awasthi P, Butcher DO, Anver MR, Golubeva YG, Bamford R, Zhang X, St Claire MB, Thomas C, Discepolo V, Jabri B, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (110), 13534-9, 2013.

Article Pubmed

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Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.


Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer-Alegre M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT


Cancer Cell , (24), 90-104, 2013.

Article Pubmed

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Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.


McDonnell SR, Hwang SR, Rolland D, Murga-Zamalloa C, Basrur V, Conlon KP, Fermin D, Wolfe T, Raskind A, Ruan C, Jiang J, Thomas C, Hogaboam CM, Burant CF, Elenitoba-Johnson KS, Lim MS


Blood , (122), 958-68, 2013.

Article Pubmed

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Identification of potent Yes1 kinase inhibitors using a library screening approach.


Patel PR, Sun H, Li SQ, Shen M, Khan J, Thomas C, Davis MI


Bioorg. Med. Chem. Lett. , (23), 4398-403, 2013.

Article Pubmed

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