Program

113
16
6
3
3

Journal Year Published

2
12
5
13
10
12
12
12
7
5
15
10
1

Author

116
182
174
134
134
125
118
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

55
45
28
19
12
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

12
9
6
6
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2

NCATS Publications

A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats.


Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin C, Eskay R, Ciccocioppo R, Zheng W, Heilig M


J. Neurosci. , (33), 10132-42, 2013.

Article Pubmed

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A homogenous luminescence assay reveals novel inhibitors for giardia lamblia carbamate kinase.


Chen C, Southall N, Galkin A, Lim K, Marugan J, Kulakova L, Shinn P, van Leer D, Zheng W, Herzberg O


Curr Chem Genomics , (6), 93-102, 2012.

Article Pubmed

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Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins.


Casson L, Howell L, Mathews LA, Ferrer-Alegre M, Southall N, Guha R, Keller JM, Thomas C, Siskind LJ, Beverly LJ


PLoS ONE , (8), e54525, 2013.

Article Pubmed

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A high-throughput screening assay using Krabbe disease patient cells.


Ribbens J, Whiteley G, Furuya H, Southall N, Hu X, Marugan J, Ferrer-Alegre M, Maegawa GH


Anal. Biochem. , (434), 15-25, 2013.

Article Pubmed

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δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.


Xu M, Liu K, Swaroop M, Porter FD, Sidhu R, Firnkes S, Finkes S, Ory DS, Marugan J, Xiao J, Southall N, Pavan WJ, Davidson C, Walkley SU, Remaley AT, Baxa U, Sun W, McKew JC, Austin C, Zheng W


J. Biol. Chem. , (287), 39349-60, 2012.

Article Pubmed

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.


Anastasiou D, et al.


Nat. Chem. Biol. , (8), 839-47, 2012.

Article Pubmed

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Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction.


Cunningham L, Finckbeiner S, Hyde RK, Southall N, Marugan J, Yedavalli VR, Dehdashti SJ, Reinhold WC, Alemu L, Zhao L, Yeh JR, Sood R, Pommier Y, Austin C, Jeang KT, Zheng W, Liu P


Proc. Natl. Acad. Sci. U.S.A. , (109), 14592-7, 2012.

Article Pubmed

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