Program

125
5
3
1
1

Journal Year Published

1
15
11
11
8
18
12
8
5
11
8
13
2
2

Author

125
182
174
134
134
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

58
49
44
23
14
4
4
1
1
1

Keyword

63
33
27
26
22
21
21
20
14
13
12
10
10
10
9
8
8
8
7
7

Journal

23
15
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1

NCATS Publications

Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.


Luci D, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman TR, Maloney DJ


J. Med. Chem. , (57), 495-506, 2014.

Article Pubmed

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A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding.


McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA


Anal Bioanal Chem , (406), 1867-75, 2014.

Article Pubmed

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Inhibition of DNA glycosylases via small molecule purine analogs.


Jacobs AC, Calkins MJ, Jadhav A, Dorjsuren D, Maloney D, Simeonov A, Jaruga P, Dizdaroglu M, McCullough AK, Lloyd RS


PLoS ONE , (8), e81667, 2013.

Article Pubmed

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Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.


Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ


Bioorg. Med. Chem. Lett. , (23), 5660-6, 2013.

Article Pubmed

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Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion.


Srinivasan P, Yasgar A, Luci D, Beatty WL, Hu X, Andersen J, Narum DL, Moch JK, Sun H, Haynes JD, Maloney DJ, Jadhav A, Simeonov A, Miller LH


Nat Commun , (4), 2261, 2013.

Article Pubmed

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Are hERG channel blockers also phospholipidosis inducers?


Sun H, Xia M, Shahane SA, Jadhav A, Austin C, Huang R


Bioorg. Med. Chem. Lett. , (23), 4587-90, 2013.

Article Pubmed

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Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy.


Hoobler EK, Rai Bantukallu G, Warrilow AG, Perry SC, Smyrniotis CJ, Jadhav A, Simeonov A, Parker JE, Kelly DE, Maloney DJ, Kelly SL, Holman TR


PLoS ONE , (8), e65928, 2013.

Article Pubmed

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3-substituted indole inhibitors against Francisella tularensis FabI identified by structure-based virtual screening.


Hu X, Compton JR, Abdulhameed MD, Marchand CL, Robertson KL, Leary DH, Jadhav A, Hershfield JR, Wallqvist A, Friedlander AM, Legler PM


J. Med. Chem. , (56), 5275-87, 2013.

Article Pubmed

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