Program

82
22
4
3
1
1

Journal Year Published

1
17
12
19
13
8
7
8
2
1

Author

88
182
174
134
134
125
118
116
114
108
86
81
73
56
51
50
43
43
42
34

Category

56
31
27
6
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.


Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer-Alegre M, Lengyel E


Nat Commun , (6), 6220, 2015.

Article Pubmed

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The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.


Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer-Alegre M, Dowling J, Xu L, Han R, Xu H


Nat. Med. , (20), 1187-92, 2014.

Article Pubmed

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Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.


Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer-Alegre M, Joshi S, Nerle S, Sandy P, Normant E, Thomas C, Staudt LM


Proc. Natl. Acad. Sci. U.S.A. , (111), 11365-70, 2014.

Article Pubmed

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A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.


Ferrer-Alegre M, Corneo B, Davis J, Wan Q, Miyagishima KJ, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K


Stem Cells Transl Med , (3), 911-22, 2014.

Article Pubmed

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Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.


Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer-Alegre M, Javitch JA, Beuming T, Shi L, Southall N, Marugan J, Sibley DR


Mol. Pharmacol. , (86), 96-105, 2014.

Article Pubmed

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Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.


Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer-Alegre M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R


J. Biol. Chem. , (289), 16349-61, 2014.

Article Pubmed

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Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.


Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer-Alegre M, Titus S, Zheng W, Sibley DR, Marugan J


J. Med. Chem. , (57), 3450-63, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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