Program

84
25
4
3
1
1
1

Journal Year Published

7
17
12
19
13
8
7
8
2
1

Author

94
183
175
144
135
127
119
118
115
108
87
81
77
57
52
50
45
44
42
34

Category

57
31
27
7
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.


Laurent LC, et al.


J Extracell Vesicles , (4), 26533, 2015.

Article Pubmed

Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays?


Sittampalam S, Eglen R, Ferguson S, Maynes JT, Olden K, Schrader L, Shelper T, Ferrer-Alegre M


Assay Drug Dev Technol , (13), 254-61, 2015.

Article Pubmed

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.


He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang A, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer-Alegre M, Zheng W, Chayama K, Marugan J, Liang TJ


Sci Transl Med , (7), 282ra49, 2015.

Article Pubmed

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Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.


Wang W, Gao Q, Yang M, Zhang X, Yu L, Lawas M, Li X, Bryant-Genevier M, Southall N, Marugan J, Ferrer-Alegre M, Xu H


Proc. Natl. Acad. Sci. U.S.A. , (112), E1373-81, 2015.

Article Pubmed

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Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing.


Camargo LM, Zhang XD, Loerch P, Caceres RM, Marine SD, Uva P, Ferrer-Alegre M, de Rinaldis E, Stone DJ, Majercak J, Ray WJ, Yi-An C, Shearman MS, Mizuguchi K


PLoS ONE , (10), e0115369, 2015.

Article Pubmed

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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.


Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer-Alegre M, Lengyel E


Nat Commun , (6), 6220, 2015.

Article Pubmed

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The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.


Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer-Alegre M, Dowling J, Xu L, Han R, Xu H


Nat. Med. , (20), 1187-92, 2014.

Article Pubmed

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Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.


Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer-Alegre M, Joshi S, Nerle S, Sandy P, Normant E, Thomas C, Staudt LM


Proc. Natl. Acad. Sci. U.S.A. , (111), 11365-70, 2014.

Article Pubmed

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