Program

84
25
4
3
1
1
1

Journal Year Published

7
11
17
12
19
13
8
7
8
2
1

Author

105
202
181
149
140
133
133
125
123
108
95
82
78
64
63
55
50
46
43
43

Category

57
31
27
7
4
2
1
1
1

Keyword

38
21
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

9
8
6
6
6
5
3
3
3
2
2
2
2
2
2
2
2
1
1
1

NCATS Publications

USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.


Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer-Alegre M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB


Proc. Natl. Acad. Sci. U.S.A. , (113), E2945-54, 2016.

Article Pubmed

Sample image from publication page

Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens.


Guha R, Mathews Griner LA, Keller JM, Zhang X, Fitzgerald D, Antignani A, Pastan I, Thomas C, Ferrer-Alegre M


J Biomol Screen , 2016.

Article Pubmed

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Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma.


Ju W, Zhang M, Wilson K, Petrus MN, Bamford RN, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (113), 1624-9, 2016.

Article Pubmed

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Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.


Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Mathews Griner LA, Ferrer-Alegre M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, Wen X, Zhang S, Shern JF, Yohe ME, Taschner-Mandl S, Shohet JM, Thomas C, Martin SE, Ambros PF, Khan J


Oncotarget , (6), 35247-62, 2015.

Article Pubmed

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.


Mott BT, Eastman R, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer-Alegre M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas C


Sci Rep , (5), 13891, 2015.

Article Pubmed

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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.


Zhang M, Mathews Griner LA, Ju W, Duveau D, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer-Alegre M, Conlon KD, Bamford RN, O'Shea JJ, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (112), 12480-5, 2015.

Article Pubmed