Program

84
25
4
3
1
1
1

Journal Year Published

1
9
17
12
19
13
8
7
8
2
1

Author

97
185
177
145
136
127
123
118
117
108
88
81
77
58
54
50
46
46
42
37

Category

57
31
27
7
4
2
1
1
1

Keyword

38
21
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1

NCATS Publications

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.


Mott BT, Eastman R, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer-Alegre M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas C


Sci Rep , (5), 13891, 2015.

Article Pubmed

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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.


Zhang M, Mathews Griner LA, Ju W, Duveau D, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer-Alegre M, Conlon KD, Bamford RN, O'Shea JJ, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (112), 12480-5, 2015.

Article Pubmed

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.


He S, Jain P, Lin B, Ferrer-Alegre M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


ACS Comb Sci , (17), 641-52, 2015.

Article Pubmed

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Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.


Laurent LC, et al.


J Extracell Vesicles , (4), 26533, 2015.

Article Pubmed

Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays?


Sittampalam S, Eglen R, Ferguson S, Maynes JT, Olden K, Schrader L, Shelper T, Ferrer-Alegre M


Assay Drug Dev Technol , (13), 254-61, 2015.

Article Pubmed

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.


He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang A, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer-Alegre M, Zheng W, Chayama K, Marugan J, Liang TJ


Sci Transl Med , (7), 282ra49, 2015.

Article Pubmed

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Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.


Wang W, Gao Q, Yang M, Zhang X, Yu L, Lawas M, Li X, Bryant-Genevier M, Southall N, Marugan J, Ferrer-Alegre M, Xu H


Proc. Natl. Acad. Sci. U.S.A. , (112), E1373-81, 2015.

Article Pubmed

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Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing.


Camargo LM, Zhang XD, Loerch P, Caceres RM, Marine SD, Uva P, Ferrer-Alegre M, de Rinaldis E, Stone DJ, Majercak J, Ray WJ, Yi-An C, Shearman MS, Mizuguchi K


PLoS ONE , (10), e0115369, 2015.

Article Pubmed

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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.


Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer-Alegre M, Lengyel E


Nat Commun , (6), 6220, 2015.

Article Pubmed

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