Program

99
92
5
3
2
1
1

Journal Year Published

11
16
11
20
10
8
9
10
12
12
10
12
4

Author

145
185
178
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
43
32
19
18
16
15
15
14
13
13
12
12
12
11
11
10
10
10
9

Journal

16
13
12
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2

NCATS Publications

NMDAR inhibition-independent antidepressant actions of ketamine metabolites.


Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas C, Zarate CA, Gould TD


Nature , (533), 481-6, 2016.

Article Pubmed

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Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model.


Papaleo F, Yang F, Paterson C, Palumbo S, Carr GV, Wang Y, Floyd K, Huang W, Thomas C, Chen J, Weinberger DR, Law AJ


J. Neurosci. , (36), 4859-75, 2016.

Article Pubmed

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Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens.


Guha R, Mathews Griner LA, Keller JM, Zhang X, Fitzgerald D, Antignani A, Pastan I, Thomas C, Ferrer-Alegre M


J Biomol Screen , 2016.

Article Pubmed

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RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.


Baranello L, Wojtowicz D, Cui K, Devaiah BN, Chung HJ, Chan-Salis KY, Guha R, Wilson K, Zhang X, Zhang H, Piotrowski J, Thomas C, Singer DS, Pugh BF, Pommier Y, Przytycka TM, Kouzine F, Lewis BA, Zhao K, Levens D


Cell , (165), 357-71, 2016.

Article Pubmed

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Structure Property Relationships of Carboxylic Acid Isosteres.


Lassalas P, Gay B, Lasfargeas C, James MJ, Tran V, Vijayendran KG, Brunden KR, Kozlowski MC, Thomas C, Smith AB, Huryn DM, Ballatore C


J. Med. Chem. , (59), 3183-203, 2016.

Article Pubmed

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Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants.


Smith SJ, Pauly GT, Akram A, Melody K, Rai Bantukallu G, Maloney DJ, Ambrose Z, Thomas C, Schneider JT, Hughes SH


Retrovirology , (13), 11, 2016.

Article Pubmed

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Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma.


Ju W, Zhang M, Wilson K, Petrus MN, Bamford RN, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (113), 1624-9, 2016.

Article Pubmed

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Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1.


Ali-Rahmani F, FitzGerald DJ, Martin S, Patel P, Prunotto M, Ormanoglu P, Thomas C, Pastan I


Cancer Res. , (76), 1560-8, 2016.

Article Pubmed

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.


Doyle JJ, Doyle AJ, Wilson NK, Habashi JP, Bedja D, Whitworth RE, Lindsay ME, Schoenhoff F, Myers L, Huso N, Bachir S, Squires O, Rusholme B, Ehsan H, Huso D, Thomas C, Caulfield MJ, Van Eyk JE, Judge DP, Dietz HC, GenTAC Registry Consortium , MIBAVA Leducq Consortium


Elife , (4), 2015.

Article Pubmed

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Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.


Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Mathews Griner LA, Ferrer-Alegre M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, Wen X, Zhang S, Shern JF, Yohe ME, Taschner-Mandl S, Shohet JM, Thomas C, Martin SE, Ambros PF, Khan J


Oncotarget , (6), 35247-62, 2015.

Article Pubmed