Program

164
16
7
5
3
3
2

Journal Year Published

7
23
16
20
13
26
17
13
8
16
8
10
4
2

Author

185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

79
74
72
29
15
12
6
1
1

Keyword

88
41
35
30
29
24
23
20
15
14
14
13
13
13
10
10
9
9
8
8

Journal

24
18
11
6
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2

NCATS Publications

Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.


Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall M, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A


J. Biol. Chem. , 2016.

Article Pubmed

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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.


Xu M, Lee E, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael S, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H


Nat. Med. , (22), 1101-1107, 2016.

Article Pubmed

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Good Cell Culture Practice for stem cells and stem-cell-derived models.


Pamies D, Bal-Price A, Simeonov A, Tagle D, Allen D, Gerhold D, Yin D, Pistollato F, Inutsuka T, Sullivan K, Stacey G, Salem H, Leist M, Daneshian M, Vemuri MC, McFarland R, Coecke S, Fitzpatrick SC, Lakshmipathy U, Mack A, Wang WB, Daiju Y, Sekino Y, Kanda Y, Smirnova L, Hartung T


ALTEX , 2016.

Article Pubmed

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Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.


Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales S, Mott BT, Rai Bantukallu G, Jansen DJ, Henderson M, Urban DJ, Hall M, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X


Cell Chem Biol , (23), 769-81, 2016.

Article Pubmed

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Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.


Deschamps JD, Ogunsola AF, Jameson JB, Yasgar A, Flitter BA, Freedman CJ, Melvin JA, Nguyen JV, Maloney DJ, Jadhav A, Simeonov A, Bomberger JM, Holman TR


Biochemistry , (55), 3329-40, 2016.

Article Pubmed

Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors.


Anantpadma M, Kouznetsova J, Wang H, Huang R, Kolokoltsov A, Guha R, Lindstrom AR, Shtanko O, Simeonov A, Maloney DJ, Maury W, LaCount DJ, Jadhav A, Davey RA


Antimicrob. Agents Chemother. , (60), 4471-81, 2016.

Article Pubmed

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In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agents.


Patel PR, Sun W, Kim M, Huang X, Sanderson P, Tanaka TQ, McKew JC, Simeonov A, Williamson KC, Zheng W, Huang W


Bioorg. Med. Chem. Lett. , (26), 2907-11, 2016.

Article Pubmed

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