Program

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Journal Year Published

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Author

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94
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57
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Category

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19
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Keyword

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Journal

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NCATS Publications

A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.


Ferrer-Alegre M, Corneo B, Davis J, Wan Q, Miyagishima KJ, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K


Stem Cells Transl Med , (3), 911-22, 2014.

Article Pubmed

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Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.


Hoskins JW, Ofori LO, Chen C, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan J, Zheng W, Austin C, Disney MD, Miller BL, Thornton CA


Nucleic Acids Res. , (42), 6591-602, 2014.

Article Pubmed

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Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.


Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer-Alegre M, Javitch JA, Beuming T, Shi L, Southall N, Marugan J, Sibley DR


Mol. Pharmacol. , (86), 96-105, 2014.

Article Pubmed

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Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.


Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer-Alegre M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R


J. Biol. Chem. , (289), 16349-61, 2014.

Article Pubmed

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Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.


Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer-Alegre M, Titus S, Zheng W, Sibley DR, Marugan J


J. Med. Chem. , (57), 3450-63, 2014.

Article Pubmed

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Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.


Ottinger E, Kao ML, Carrillo-Carrasco N, Yanjanin N, Shankar RK, Janssen M, Brewster M, Scott I, Xu X, Cradock J, Terse P, Dehdashti SJ, Marugan J, Zheng W, Portilla Weingarten L, Hubbs A, Pavan WJ, Heiss J, Vite CH, Walkley SU, Ory DS, Silber SA, Porter FD, Austin C, McKew JC


Curr Top Med Chem , (14), 330-9, 2014.

Pubmed

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Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor.


Patnaik S, Marugan J, Liu K, Zheng W, Southall N, Dehdashti SJ, Thorsell A, Heilig M, Bell L, Zook M, Eskay B, Brimacombe K, Austin C


J. Med. Chem. , (56), 9045-56, 2013.

Article Pubmed

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A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice.


Neumann S, Nir EA, Eliseeva E, Huang W, Marugan J, Xiao J, Dulcey AE, Gershengorn MC


Endocrinology , (155), 310-4, 2014.

Article Pubmed

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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.


Childs-Disney JL, Stepniak-Konieczna E, Tran T, Yildirim I, Park H, Chen C, Hoskins J, Southall N, Marugan J, Patnaik S, Zheng W, Austin C, Schatz GC, Sobczak K, Thornton CA, Disney MD


Nat Commun , (4), 2044, 2013.

Article Pubmed

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