Program

91
32
7
2
1

Journal Year Published

1
4
2
2
5
7
4
5
9
12
23
23
8
2
1

Author

108
182
174
134
134
125
118
116
114
88
86
81
73
56
51
50
43
43
42
34

Category

64
43
16
15
8
7
6
1

Keyword

52
36
32
25
22
20
19
12
12
11
11
10
9
9
8
8
8
8
8
8

Journal

12
9
8
7
6
5
5
4
3
2
2
2
2
2
2
2
2
2
1
1

NCATS Publications

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Boxer MB, Jiang J, Vander Heiden MG, Shen M, Skoumbourdis AP, Southall N, Veith H, Leister W, Austin C, Park HW, Inglese J, Cantley LC, Auld DS, Thomas C


J. Med. Chem. , (53), 1048-55, 2010.

Article Pubmed

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Identification of small molecule compounds that inhibit the HIF-1 signaling pathway.


Xia M, Bi K, Huang R, Cho MH, Sakamuru S, Miller SC, Li H, Sun Y, Printen J, Austin C, Inglese J


Mol. Cancer , (8), 117, 2009.

Article Pubmed

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Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.


Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin C, Thomas C, Shoichet BK, Maloney DJ


J. Med. Chem. , (53), 52-60, 2010.

Article Pubmed

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Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.


Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin C, Lloyd DG, Auld DS


Nat. Biotechnol. , (27), 1050-5, 2009.

Article Pubmed

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Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk).


Mott BT, Tanega C, Shen M, Maloney DJ, Shinn P, Leister W, Marugan J, Inglese J, Austin C, Misteli T, Auld DS, Thomas C


Bioorg. Med. Chem. Lett. , (19), 6700-5, 2009.

Article Pubmed

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The pilot phase of the NIH Chemical Genomics Center.


Thomas C, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan J, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin C


Curr Top Med Chem , (9), 1181-93, 2009.

Pubmed

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Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.


Rai Bantukallu G, Sayed AA, Lea WA, Luecke HF, Chakrapani H, Prast-Nielsen S, Jadhav A, Leister W, Shen M, Inglese J, Austin C, Keefer L, Arnér ES, Simeonov A, Maloney DJ, Williams DL, Thomas C


J. Med. Chem. , (52), 6474-83, 2009.

Article Pubmed

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