Program

116
16
6
4
3

Journal Year Published

1
8
12
5
13
10
12
12
12
7
5
15
10
1

Author

123
185
177
145
136
127
118
117
108
97
88
81
77
58
54
50
46
46
42
37

Category

56
45
28
20
13
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

12
9
6
6
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2

NCATS Publications

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.


He S, Jain P, Lin B, Ferrer-Alegre M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


ACS Comb Sci , (17), 641-52, 2015.

Article Pubmed

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Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.


Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin C, Simeonov A, Sittampalam S, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas C


PLoS ONE , (10), e0130796, 2015.

Article Pubmed

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Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.


He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang A, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer-Alegre M, Zheng W, Chayama K, Marugan J, Liang TJ


Sci Transl Med , (7), 282ra49, 2015.

Article Pubmed

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Mitochondrial DNA damage by bleomycin induces AML cell death.


Yeung M, Hurren R, Nemr C, Wang X, Hershenfeld S, Gronda M, Liyanage S, Wu Y, Augustine J, Lee EA, Spagnuolo PA, Southall N, Chen C, Zheng W, Jeyaraju DV, Minden MD, Laposa R, Schimmer AD


Apoptosis , (20), 811-20, 2015.

Article Pubmed

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Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.


Wang W, Gao Q, Yang M, Zhang X, Yu L, Lawas M, Li X, Bryant-Genevier M, Southall N, Marugan J, Ferrer-Alegre M, Xu H


Proc. Natl. Acad. Sci. U.S.A. , (112), E1373-81, 2015.

Article Pubmed

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BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.


Howe EA, de Souza A, Lahr DL, Chatwin S, Montgomery P, Alexander BR, Nguyen T, Cruz Y, Stonich DA, Walzer G, Rose JT, Picard SC, Liu Z, Rose JN, Xiang X, Asiedu J, Durkin D, Levine J, Yang JJ, Schürer SC, Braisted J, Southall N, Southern MR, Chung TD, Brudz S, Tanega C, Schreiber SL, Bittker JA, Guha R, Clemons PA


Nucleic Acids Res. , (43), D1163-70, 2015.

Article Pubmed

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Discovery of novel antigiardiasis drug candidates.


Kulakova L, Galkin A, Chen C, Southall N, Marugan J, Zheng W, Herzberg O


Antimicrob. Agents Chemother. , (58), 7303-11, 2014.

Article Pubmed

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