Program

163
15
7
5
3
3
2

Journal Year Published

4
23
16
20
13
26
17
13
8
16
8
10
4
2

Author

182
174
134
134
125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

79
74
72
29
14
12
6
1
1

Keyword

88
41
35
30
29
24
23
20
15
14
14
13
13
13
10
10
9
9
8
8

Journal

24
18
11
6
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2

NCATS Publications

Literature Search and Review.


Simeonov A, Auld D


Assay Drug Dev Technol , (15), 134-140, .

Article Pubmed

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Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform.


Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M


Toxicology , 2017.

Article Pubmed

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A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation.


Lessing D, Dial TO, Wei C, Payer B, Carrette LL, Kesner B, Szanto A, Jadhav A, Maloney DJ, Simeonov A, Theriault J, Hasaka T, Bedalov A, Bartolomei MS, Lee JT


Proc. Natl. Acad. Sci. U.S.A. , (113), 14366-14371, 2016.

Article Pubmed

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Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".


Houck KA, Judson RS, Knudsen TB, Martin MT, Richard AM, Crofton KM, Simeonov A, Paules RS, Bucher JR, Thomas RS


Environ. Health Perspect. , (125), A8-A11, 2017.

Article Pubmed

Pharos: Collating protein information to shed light on the druggable genome.


Nguyen T, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, Hersey A, Holmes J, Jensen LJ, Karlsson A, Liu G, Ma'ayan A, Mandava G, Mani S, Mehta S, Overington J, Patel J, Rouillard AD, Schürer S, Sheils T, Simeonov A, Sklar LA, Southall N, Ursu O, Vidovic D, Waller A, Yang J, Jadhav A, Oprea TI, Guha R


Nucleic Acids Res. , (45), D995-D1002, 2017.

Article Pubmed

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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.


Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall M, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A


J. Biol. Chem. , 2016.

Article Pubmed

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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.


Xu M, Lee E, Wen Z, Cheng Y, Huang W, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael S, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H


Nat. Med. , (22), 1101-1107, 2016.

Article Pubmed

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