Program

84
10
4
1

Journal Year Published

2
10
9
18
6
12
7
11
5
3
3

Author

86
182
174
134
134
125
118
116
114
108
88
81
73
56
51
50
43
43
42
34

Category

59
19
19
15
7
2
1
1

Keyword

37
23
16
15
14
12
12
10
7
7
6
6
6
6
5
5
5
5
5
5

Journal

8
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1

NCATS Publications

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.


He S, Jain P, Lin B, Ferrer-Alegre M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


ACS Comb Sci , (17), 641-52, 2015.

Article Pubmed

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Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.


He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang A, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer-Alegre M, Zheng W, Chayama K, Marugan J, Liang TJ


Sci Transl Med , (7), 282ra49, 2015.

Article Pubmed

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Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.


Wang W, Gao Q, Yang M, Zhang X, Yu L, Lawas M, Li X, Bryant-Genevier M, Southall N, Marugan J, Ferrer-Alegre M, Xu H


Proc. Natl. Acad. Sci. U.S.A. , (112), E1373-81, 2015.

Article Pubmed

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Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.


Lu X, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan J, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW


Sci Transl Med , (6), 268ra178, 2014.

Article Pubmed

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Discovery of novel antigiardiasis drug candidates.


Kulakova L, Galkin A, Chen C, Southall N, Marugan J, Zheng W, Herzberg O


Antimicrob. Agents Chemother. , (58), 7303-11, 2014.

Article Pubmed

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Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs.


Aflaki E, Stubblefield BK, Maniwang E, Lopez G, Moaven N, Goldin E, Marugan J, Patnaik S, Dutra A, Southall N, Zheng W, Tayebi N, Sidransky E


Sci Transl Med , (6), 240ra73, 2014.

Article Pubmed

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Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.


Yu D, Swaroop M, Wang M, Baxa U, Yang R, Yan Y, Coksaygan T, DeTolla L, Marugan J, Austin C, McKew JC, Gong DW, Zheng W


J Biomol Screen , (19), 1164-73, 2014.

Article Pubmed

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A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.


Ferrer-Alegre M, Corneo B, Davis J, Wan Q, Miyagishima KJ, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K


Stem Cells Transl Med , (3), 911-22, 2014.

Article Pubmed

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