Program

131
30
10
7
7
3
2
2
1

Journal Year Published

2
6
9
10
7
7
12
13
17
17
12
33
21
8
3
3

Author

181
202
149
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

78
66
29
29
23
12
8
8
6
4
1

Keyword

102
49
36
35
32
24
23
20
17
16
14
14
13
12
12
11
11
10
10
10

Journal

12
10
9
8
8
7
7
6
5
5
4
4
4
3
3
3
3
3
2
2

NCATS Publications

Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.


Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou YH, Jack JR, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif AA, Austin C, Tice RR, Rusyn I, Wright FA


Environ. Health Perspect. , (123), 458-66, 2015.

Article Pubmed

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Identification of small molecule modulators of gene transcription with anticancer activity.


Tran TA, Kouznetsova J, Varghese D, Huang R, Huang W, Becker M, Austin C, Inglese J, Johnson RL, Martinez ED


ACS Chem. Biol. , (9), 2603-11, 2014.

Article Pubmed

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Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.


Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, Shinn P, Simeonov A, Dix DJ, Austin C, Kavlock RJ, Tice RR, Xia M


Sci Rep , (4), 5664, 2014.

Article Pubmed

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Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.


Yu D, Swaroop M, Wang M, Baxa U, Yang R, Yan Y, Coksaygan T, DeTolla L, Marugan J, Austin C, McKew JC, Gong DW, Zheng W


J Biomol Screen , (19), 1164-73, 2014.

Article Pubmed

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Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.


Blackford JA, Brimacombe K, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin C, Simons SS


Mol. Endocrinol. , (28), 1194-206, 2014.

Article Pubmed

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Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.


Hoskins JW, Ofori LO, Chen C, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan J, Zheng W, Austin C, Disney MD, Miller BL, Thornton CA


Nucleic Acids Res. , (42), 6591-602, 2014.

Article Pubmed

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Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.


Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin C, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN


Cancer Res. , (74), 2520-32, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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