Program

585
109
107
103
36
3
769
26
22
16
11
10
10
9
4
1

Journal Year Published

31
94
73
129
80
82
75
65
51
40
40
29
14
4
3
2

Author

183
155
142
134
127
118
118
114
108
93
86
81
71
57
52
50
43
43
42
34

Category

340
309
283
84
69
49
21
19
12
9
3
2

Keyword

367
212
114
112
88
79
74
70
66
59
54
53
46
45
40
40
37
36
35
35

Journal

48
37
30
28
25
24
20
16
14
14
14
13
12
11
10
10
9
9
9
8

NCATS Publications

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).


Sommers JA, Kulikowicz T, Croteau DL, Dexheimer T, Dorjsuren D, Jadhav A, Maloney DJ, Simeonov A, Bohr VA, Brosh RM


PLoS ONE , (14), e0210525, 2019.

Article Pubmed

Toxicogenomics: A 2020 Vision.


Liu Z, Huang R, Roberts R, Tong W


Trends Pharmacol. Sci. , (40), 92-103, 2019.

Article Pubmed

Sample image from publication page

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.


Iniguez AB, Alexe G, Wang EJ, Roti G, Patel S, Chen L, Kitara S, Conway A, Robichaud AL, Stolte B, Bandopadhayay P, Goodale A, Pantel S, Lee Y, Cheff D, Hall M, Guha R, Davis MI, Menard M, Nasholm N, Weiss WA, Qi J, Beroukhim R, Piccioni F, Johannessen C, Stegmaier K


Cancer Cell , (34), 922-938.e7, 2018.

Article Pubmed

Sample image from publication page

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

Sample image from publication page

KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations.


Liu X, Zhang SM, McGeary MK, Krykbaeva I, Lai L, Jansen DJ, Kales S, Simeonov A, Hall M, Kelly DP, Bosenberg MW, Yan Q


Mol. Cancer Ther. , 2018.

Article Pubmed

AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice.


Hakim C, Wasala NB, Nelson CE, Wasala LP, Yue Y, Louderman JA, Lessa TB, Dai A, Zhang K, Jenkins GJ, Nance ME, Pan X, Kodippili K, Yang N, Chen SJ, Gersbach CA, Duan D


JCI Insight , (3), 2018.

Article Pubmed

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.


Highland JN, Morris P, Zanos P, Lovett J, Ghosh S, Wang A, Zarate CA, Thomas C, Moaddel R, Gould TD


J. Psychopharmacol. (Oxford) , 269881118812095, 2018.

Article Pubmed