Program

92
90
5
3
2
1

Journal Year Published

16
11
20
10
8
9
10
12
12
10
12
4

Author

134
182
174
134
125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
41
30
19
18
16
15
15
14
13
13
12
12
11
11
10
10
10
9
9

Journal

14
13
11
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2

NCATS Publications

A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm.


Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer-Alegre M, Chaperot L, Plumas J, Jaffe ES, Thomas C, Reizis B, Staudt LM


Cancer Cell , (30), 764-778, 2016.

Article Pubmed

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Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.


Gui DY, Sullivan LB, Luengo A, Hosios AM, Bush LN, Gitego N, Davidson SM, Freinkman E, Thomas C, Vander Heiden MG


Cell Metab. , (24), 716-727, 2016.

Article Pubmed

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Drug resistant integrase mutants cause aberrant HIV integrations.


Varadarajan J, McWilliams MJ, Mott BT, Thomas C, Smith SJ, Hughes SH


Retrovirology , (13), 71, 2016.

Article Pubmed

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Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.


Antignani A, Mathews Griner L, Guha R, Simon N, Pasetto M, Keller J, Huang M, Angelus E, Pastan I, Ferrer-Alegre M, FitzGerald DJ, Thomas C


PLoS ONE , (11), e0161415, 2016.

Article Pubmed

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Cancer network activity associated with therapeutic response and synergism.


Serra-Musach J, Mateo F, Capdevila-Busquets E, de Garibay GR, Zhang X, Guha R, Thomas C, Grueso J, Villanueva A, Jaeger S, Heyn H, Vizoso M, Pérez H, Cordero A, Gonzalez-Suarez E, Esteller M, Moreno-Bueno G, Tjärnberg A, Lázaro C, Serra V, Arribas J, Benson M, Gustafsson M, Ferrer-Alegre M, Aloy P, Pujana MÀ


Genome Med , (8), 88, 2016.

Article Pubmed

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Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.


Wang W, Nguyen LT, Burlak C, Chegini F, Guo F, Chataway T, Ju S, Fisher OS, Miller DW, Datta D, Wu F, Wu CX, Landeru A, Wells JA, Cookson MR, Boxer MB, Thomas C, Gai WP, Ringe D, Petsko GA, Hoang QQ


Proc. Natl. Acad. Sci. U.S.A. , (113), 9587-92, 2016.

Article Pubmed

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Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.


Kasbekar M, Fischer G, Mott BT, Yasgar A, Hyvönen M, Boshoff HI, Abell C, Barry CE, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (113), 7503-8, 2016.

Article Pubmed

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FBXO10 deficiency and BTK activation upregulate BCL2 expression in mantle cell lymphoma.


Li Y, Bouchlaka MN, Wolff J, Grindle KM, Lu L, Qian S, Zhong X, Pflum N, Jobin P, Kahl BS, Eickhoff JC, Wuerzberger-Davis SM, Miyamoto S, Thomas C, Yang DT, Capitini CM, Rui L


Oncogene , 2016.

Article Pubmed

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.


Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas C, Zarate CA, Gould TD


Nature , (533), 481-6, 2016.

Article Pubmed

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