Program

99
92
5
3
2
1
1

Journal Year Published

3
12
16
11
20
10
8
9
10
12
12
10
12
4

Author

149
201
181
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
43
32
19
18
16
15
15
14
13
13
12
12
12
11
11
10
10
10
9

Journal

16
13
12
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2

NCATS Publications

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.


Calabrese D, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas C, Mock BA, Schneekloth JS


Nucleic Acids Res. , 2018.

Article Pubmed

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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.


Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas C, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T


Nat. Med. , (23), 1362-1368, 2017.

Article Pubmed

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Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.


Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris P, Thomas C, Possemato R, Vander Heiden MG, Papagiannakopoulos T


Elife , (6), 2017.

Article Pubmed

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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.


Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau D, Morris P, Zhao J, Thomas C, Monje M


Nature , (549), 533-537, 2017.

Article Pubmed

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Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.


Heske CM, Davis MI, Baumgart JT, Wilson K, Gormally MV, Chen L, Zhang X, Ceribelli M, Duveau D, Guha R, Ferrer-Alegre M, Arnaldez FI, Ji J, Tran HL, Zhang Y, Mendoza A, Helman LJ, Thomas C


Clin. Cancer Res. , 2017.

Article Pubmed

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Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites.


Morris P, Moaddel R, Zanos P, Moore CE, Gould T, Zarate CA, Thomas C


Org. Lett. , (19), 4572-4575, 2017.

Article Pubmed

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Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.


Lionakis MS, Dunleavy K, Roschewski M, Widemann BC, Butman JA, Schmitz R, Yang Y, Cole DE, Melani C, Higham CS, Desai JV, Ceribelli M, Chen L, Thomas C, Little RF, Gea-Banacloche J, Bhaumik S, Stetler-Stevenson M, Pittaluga S, Jaffe ES, Heiss J, Lucas N, Steinberg SM, Staudt LM, Wilson WH


Cancer Cell , (31), 833-843.e5, 2017.

Article Pubmed

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Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.


Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer-Alegre M, Rudloff U


J Transl Med , (15), 92, 2017.

Article Pubmed

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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.


Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer-Alegre M, Shern JF, Zhao K, Thomas C, Khan J


Cancer Discov , 2017.

Article Pubmed