Program

56
11
4
2
1
1
1
1

Journal Year Published

1
6
1
7
5
6
8
7
6
5
5

Author

57
183
175
144
135
127
119
118
115
108
94
87
81
77
52
50
45
44
42
34

Category

22
18
15
14
7
5
3
1
1

Keyword

32
15
15
13
11
10
10
9
8
8
7
7
7
6
6
6
6
6
5
5

Journal

9
6
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

TOP2A is overexpressed and is a therapeutic target for adrenocortical carcinoma.


Jain M, Zhang L, He M, Zhang Y, Shen M, Kebebew E


Endocr. Relat. Cancer , (20), 361-70, 2013.

Article Pubmed

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A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.


Davis MI, Sasaki AT, Shen M, Emerling BM, Thorne N, Michael S, Pragani R, Boxer M, Sumita K, Takeuchi K, Auld DS, Li Z, Cantley LC, Simeonov A


PLoS ONE , (8), e54127, 2013.

Article Pubmed

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Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors.


Duveau D, Hu X, Walsh MJ, Shukla S, Skoumbourdis AP, Boxer MB, Ambudkar SV, Shen M, Thomas C


Bioorg. Med. Chem. Lett. , (23), 682-6, 2013.

Article Pubmed

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.


Anastasiou D, et al.


Nat. Chem. Biol. , (8), 839-47, 2012.

Article Pubmed

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A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.


Morgan HP, Walsh MJ, Blackburn EA, Wear MA, Boxer MB, Shen M, Veith H, McNae IW, Nowicki MW, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD


Biochem. J. , (448), 67-72, 2012.

Article Pubmed

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Application of a homogenous membrane potential assay to assess mitochondrial function.


Sakamuru S, Li X, Attene-Ramos MS, Huang R, Lu J, Shou L, Shen M, Tice RR, Austin C, Xia M


Physiol. Genomics , (44), 495-503, 2012.

Article Pubmed

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Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.


Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas C, Filizola M, Springer TA, Coller BS


Sci Transl Med , (4), 125ra32, 2012.

Article Pubmed

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