Program

82
22
4
3
1
1

Journal Year Published

1
17
12
19
13
8
7
8
2
1

Author

88
182
174
134
134
125
118
116
114
108
86
81
73
56
51
50
43
43
42
34

Category

56
31
27
6
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Large-scale pharmacological profiling of 3D tumor models of cancer cells.


Mathews Griner LA, Zhang X, Guha R, McKnight C, Goldlust IS, Lal-Nag M, Wilson K, Michael S, Titus S, Shinn P, Thomas C, Ferrer-Alegre M


Cell Death Dis , (7), e2492, 2016.

Article Pubmed

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ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.


Abera MB, Xiao J, Nofziger J, Titus S, Southall N, Zheng W, Moritz KE, Ferrer-Alegre M, Cherry JJ, Androphy EJ, Wang A, Xu X, Austin C, Fischbeck KH, Marugan J, Burnett BG


JCI Insight , (1), e88427, 2016.

Article Pubmed

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A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm.


Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer-Alegre M, Chaperot L, Plumas J, Jaffe ES, Thomas C, Reizis B, Staudt LM


Cancer Cell , (30), 764-778, 2016.

Article Pubmed

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Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition.


Estrada LD, Chamorro D, Yañez MJ, Gonzalez M, Leal N, von Bernhardi R, Dulcey AE, Marugan J, Ferrer-Alegre M, Soto C, Zanlungo S, Inestrosa NC, Alvarez AR


J. Alzheimers Dis. , (54), 1193-1205, 2016.

Article Pubmed

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Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.


Antignani A, Mathews Griner L, Guha R, Simon N, Pasetto M, Keller J, Huang M, Angelus E, Pastan I, Ferrer-Alegre M, FitzGerald DJ, Thomas C


PLoS ONE , (11), e0161415, 2016.

Article Pubmed

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Cancer network activity associated with therapeutic response and synergism.


Serra-Musach J, Mateo F, Capdevila-Busquets E, de Garibay GR, Zhang X, Guha R, Thomas C, Grueso J, Villanueva A, Jaeger S, Heyn H, Vizoso M, Pérez H, Cordero A, Gonzalez-Suarez E, Esteller M, Moreno-Bueno G, Tjärnberg A, Lázaro C, Serra V, Arribas J, Benson M, Gustafsson M, Ferrer-Alegre M, Aloy P, Pujana MÀ


Genome Med , (8), 88, 2016.

Article Pubmed

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Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors.


Singh A, Venkannagari S, Oh KH, Zhang Y, Liu L, Rohde JM, Nimmagadda S, Sudini K, Brimacombe K, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, A Mensah G, Wang Z, Ferrer-Alegre M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S


ACS Chem. Biol. , 2016.

Article Pubmed

Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.


Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer-Alegre M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN


J Biomol Screen , 2016.

Article Pubmed