Program

32
11
7
7
1

Journal Year Published

6
3
7
4
5
2
3
3
3
2
3
1
1

Author

43
182
174
134
134
125
118
116
114
108
88
86
81
73
56
51
50
43
42
34

Category

21
21
17
4
4
4
3
1
1

Keyword

18
9
9
8
7
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3

Journal

3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.


Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer-Alegre M, Joshi S, Nerle S, Sandy P, Normant E, Thomas C, Staudt LM


Proc. Natl. Acad. Sci. U.S.A. , (111), 11365-70, 2014.

Article Pubmed

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Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.


Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, Shinn P, Simeonov A, Dix DJ, Austin C, Kavlock RJ, Tice RR, Xia M


Sci Rep , (4), 5664, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.


Ketley A, Chen C, Li X, Arya S, Robinson TE, Granados-Riveron J, Udosen I, Morris GE, Holt I, Furling D, Chaouch S, Haworth B, Southall N, Shinn P, Zheng W, Austin C, Hayes CJ, Brook JD


Hum. Mol. Genet. , (23), 1551-62, 2014.

Article Pubmed

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Rapid identification of antifungal compounds against Exserohilum rostratum using high throughput drug repurposing screens.


Sun W, Park YD, Sugui JA, Fothergill A, Southall N, Shinn P, McKew JC, Kwon-Chung KJ, Zheng W, Williamson PR


PLoS ONE , (8), e70506, 2013.

Article Pubmed

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A homogenous luminescence assay reveals novel inhibitors for giardia lamblia carbamate kinase.


Chen C, Southall N, Galkin A, Lim K, Marugan J, Kulakova L, Shinn P, van Leer D, Zheng W, Herzberg O


Curr Chem Genomics , (6), 93-102, 2012.

Article Pubmed

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A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.


Mathews LA, Keller JM, Goodwin BL, Guha R, Shinn P, Mull R, Thomas C, de Kluyver RL, Sayers TJ, Ferrer-Alegre M


J Biomol Screen , (17), 1231-42, 2012.

Article Pubmed

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Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.


Yang Y, Shaffer AL, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, Balasubramanian S, Mathews LA, Shinn P, Guha R, Ferrer-Alegre M, Thomas C, Waldmann TA, Staudt LM


Cancer Cell , (21), 723-37, 2012.

Article Pubmed

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