Program

84
10
4
1

Journal Year Published

2
10
9
18
6
12
7
11
5
3
3

Author

86
182
174
134
134
125
118
116
114
108
88
81
73
56
51
50
43
43
42
34

Category

59
19
19
15
7
2
1
1

Keyword

37
23
16
15
14
12
12
10
7
7
6
6
6
6
5
5
5
5
5
5

Journal

8
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1

NCATS Publications

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.


Abera MB, Xiao J, Nofziger J, Titus S, Southall N, Zheng W, Moritz KE, Ferrer-Alegre M, Cherry JJ, Androphy EJ, Wang A, Xu X, Austin C, Fischbeck KH, Marugan J, Burnett BG


JCI Insight , (1), e88427, 2016.

Article Pubmed

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Synthetic non-peptide low molecular weight agonists of the relaxin receptor 1.


Agoulnik AI, Agoulnik IU, Hu X, Marugan J


Br. J. Pharmacol. , (174), 977-989, 2017.

Article Pubmed

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Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition.


Estrada LD, Chamorro D, Yañez MJ, Gonzalez M, Leal N, von Bernhardi R, Dulcey AE, Marugan J, Ferrer-Alegre M, Soto C, Zanlungo S, Inestrosa NC, Alvarez AR


J. Alzheimers Dis. , (54), 1193-1205, 2016.

Article Pubmed

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Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.


Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan J, Muro S, Li Z, Brady R, Zheng W


Stem Cells Transl Med , 2016.

Article Pubmed

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Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.


Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, Sidransky E, Marugan J, Sue CM, Krainc D


J. Neurosci. , (36), 7693-706, 2016.

Article Pubmed

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A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.


Aflaki E, Borger DK, Moaven N, Stubblefield BK, Rogers SA, Patnaik S, Schoenen FJ, Westbroek W, Zheng W, Sullivan P, Fujiwara H, Sidhu R, Khaliq ZM, Lopez GJ, Goldstein DS, Ory DS, Marugan J, Sidransky E


J. Neurosci. , (36), 7441-52, 2016.

Article Pubmed

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MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.


Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer-Alegre M, Xu H


Nat Commun , (7), 12109, 2016.

Article Pubmed

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Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.


Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang A, Xu X, Dulcey AE, Marugan J, Ferrer-Alegre M, Arav-Boger R


PLoS Pathog. , (12), e1005717, 2016.

Article Pubmed

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