Program

22
3
1
1

Journal Year Published

2
4
4
3
3
3
1
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2
1

Author

24
202
181
149
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

12
8
6
4
1

Keyword

9
5
5
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2

Journal

4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
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1

NCATS Publications

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.


Anastasiou D, et al.


Nat. Chem. Biol. , (8), 839-47, 2012.

Article Pubmed

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2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Walsh MJ, Brimacombe K, Veith H, Bougie JM, Daniel T, Leister W, Cantley LC, Israelsen WJ, Vander Heiden MG, Shen M, Auld DS, Thomas C, Boxer MB


Bioorg. Med. Chem. Lett. , (21), 6322-7, 2011.

Article Pubmed

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Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.


Hall M, Brimacombe K, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, Fales HM, Gottesman MM


J. Med. Chem. , (54), 5878-89, 2011.

Article Pubmed

Sample image from publication page