Program

17
4
2
2

Journal Year Published

4
2
8
5
7
2
2

Author

30
201
181
149
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

20
5
2
1
1

Keyword

6
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1

Journal

5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy.


Wiederhold NP, Xu X, Wang A, Najvar LK, Garvey EP, Ottinger E, Alimardanov A, Cradock J, Behnke M, Hoekstra WJ, Brand SR, Schotzinger RJ, Jaramillo R, Olivo M, Kirkpatrick WR, Patterson TF


Antimicrob. Agents Chemother. , 2018.

Article Pubmed

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.


Rolt A, Le D, Hu Z, Wang A, Shah P, Singleton M, Hughes E, Dulcey AE, He S, Imamura M, Uchida T, Chayama K, Xu X, Marugan J, Liang TJ


J. Infect. Dis. , 2018.

Article Pubmed

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban DJ, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

Sample image from publication page

Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy.


Xu X, Wang A, Latham LL, Celeste F, Ciccone C, Malicdan MC, Goldspiel B, Terse P, Cradock J, Yang N, Yorke S, McKew JC, Gahl WA, Huizing M, Carrillo N


Mol. Genet. Metab. , (122), 126-134, 2017.

Article Pubmed

Sample image from publication page

Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle.


He S, Li K, Lin B, Hu Z, Xiao J, Hu X, Wang A, Xu X, Ferrer-Alegre M, Southall N, Zheng W, Aubé J, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


J. Med. Chem. , (60), 6364-6383, 2017.

Article Pubmed

Sample image from publication page

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.


Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris P, Guha R, Klumpp-Thomas C, McKnight C, Chen YC, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG, White JM


PLoS Negl Trop Dis , (11), e0005540, 2017.

Article Pubmed

Sample image from publication page

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.


Sarathy A, Wuebbles RD, Fontelonga TM, Tarchione AR, Mathews Griner LA, Heredia DJ, Nunes AM, Duan S, Brewer PD, Van Ry T, Hennig GW, Gould TW, Dulcey AE, Wang A, Xu X, Chen C, Hu X, Zheng W, Southall N, Ferrer-Alegre M, Marugan J, Burkin DJ


Mol. Ther. , 2017.

Article Pubmed

Sample image from publication page

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.


Abera MB, Xiao J, Nofziger J, Titus S, Southall N, Zheng W, Moritz KE, Ferrer-Alegre M, Cherry JJ, Androphy EJ, Wang A, Xu X, Austin C, Fischbeck KH, Marugan J, Burnett BG


JCI Insight , (1), e88427, 2016.

Article Pubmed

Sample image from publication page