Program

99
92
5
3
2
1
1

Journal Year Published

11
16
11
20
10
8
9
10
12
12
10
12
4

Author

145
185
177
136
127
123
118
117
108
97
88
81
77
58
54
50
46
46
42
37

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
43
32
19
18
16
15
15
14
13
13
12
12
12
11
11
10
10
10
9

Journal

16
13
12
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2

NCATS Publications

Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.


Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris P, Thomas C, Zarate CA, Moaddel R, Traynelis SF, Pereira EFR, Thompson SM, Albuquerque EX, Gould TD


Proc. Natl. Acad. Sci. U.S.A. , (116), 5160-5169, 2019.

Article Pubmed

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Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.


Highland JN, Morris P, Zanos P, Lovett J, Ghosh S, Wang A, Zarate CA, Thomas C, Moaddel R, Gould TD


J. Psychopharmacol. (Oxford) , 269881118812095, 2018.

Article Pubmed

High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.


Jansson KH, Tucker JB, Stahl LE, Simmons JK, Fuller C, Beshiri ML, Agarwal S, Fang L, Hynes PG, Alilin AN, Lake R, Abbey YC, Cawley J, Tice CM, Yin J, McKnight C, Klumpp-Thomas C, Zhang X, Guha R, Hoover S, Simpson RM, Nguyen HM, Corey E, Thomas C, Proia DA, Kelly K


Sci Rep , (8), 17239, 2018.

Article Pubmed

Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.


Wilson K, Mathews-Griner LA, Williamson T, Guha R, Chen L, Shinn P, McKnight C, Michael S, Klumpp-Thomas C, Binder ZA, Ferrer-Alegre M, Gallia GL, Thomas C, Riggins GJ


SLAS Technol , 2472630318803749, 2018.

Article Pubmed

Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.


Martin SES, Tan ZW, Itkonen HM, Duveau D, Paulo JA, Janetzko J, Boutz PL, Törk L, Moss FA, Thomas C, Gygi SP, Lazarus MB, Walker S


J. Am. Chem. Soc. , (140), 13542-13545, 2018.

Article Pubmed

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Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.


Alkan HF, Walter KE, Luengo A, Madreiter-Sokolowski CT, Stryeck S, Lau AN, Al-Zoughbi W, Lewis CA, Thomas C, Hoefler G, Graier WF, Madl T, Vander Heiden MG, Bogner-Strauss JG


Cell Metab. , 2018.

Article Pubmed

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Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.


Moaddel R, Shardell M, Khadeer M, Lovett J, Kadriu B, Ravichandran S, Morris P, Yuan P, Thomas C, Gould TD, Ferrucci L, Zarate CA


Psychopharmacology (Berl.) , (235), 3017-3030, 2018.

Article Pubmed

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Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy.


Feliz-Mosquea YR, Christensen AA, Wilson AS, Westwood B, Varagic J, Meléndez GC, Schwartz AL, Chen QR, Mathews Griner L, Guha R, Thomas C, Ferrer-Alegre M, Merino MJ, Cook KL, Roberts DD, Soto-Pantoja DR


Breast Cancer Res. Treat. , (172), 69-82, 2018.

Article Pubmed

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.


Meyer SE, Muench DE, Rogers AM, Newkold TJ, Orr E, O'Brien E, Perentesis JP, Doench JG, Lal A, Morris P, Thomas C, Lieberman J, McGlinn E, Aronow BJ, Salomonis N, Grimes HL


J. Exp. Med. , (215), 2115-2136, 2018.

Article Pubmed

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