Program

55
11
4
2
1
1
1
1

Journal Year Published

6
1
7
5
6
8
7
6
5
5

Author

56
182
174
134
134
125
118
116
114
108
88
86
81
73
51
50
43
43
42
34

Category

21
18
15
14
7
5
3
1
1

Keyword

32
15
15
13
11
10
10
9
8
8
7
7
7
6
6
6
6
6
5
5

Journal

9
6
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics.


Tschapalda K, Zhang Y, Liu L, Golovnina K, Schlemper T, Eichmann TO, Lal-Nag M, Sreenivasan U, McLenithan J, Ziegler S, Sztalryd C, Lass A, Auld D, Oliver B, Waldmann H, Li Z, Shen M, Boxer MB, Beller M


EBioMedicine , (8), 49-59, 2016.

Article Pubmed

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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.


Pacold ME, et al.


Nat. Chem. Biol. , (12), 452-8, 2016.

Article Pubmed

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Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma.


Satoh K, Zhang L, Zhang Y, Chelluri R, Boufraqech M, Nilubol N, Patel D, Shen M, Kebebew E


Clin. Cancer Res. , (22), 3458-66, 2016.

Article Pubmed

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Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.


Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, Tian Z, Yu Z, Boxer MB, Kiefer JA, Copland JA, Smallridge RC, Li Z, Shen M, Kebebew E


Oncotarget , (6), 9073-85, 2015.

Article Pubmed

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Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.


Ong CC, et al.


Breast Cancer Res. , (17), 59, 2015.

Article Pubmed

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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.


Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe K, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ


Nature , (522), 216-20, 2015.

Article Pubmed

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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.


Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer-Alegre M, Lengyel E


Nat Commun , (6), 6220, 2015.

Article Pubmed

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Structure activity relationships of human galactokinase inhibitors.


Liu L, Tang M, Walsh MJ, Brimacombe K, Pragani R, Tanega C, Rohde JM, Baker H, Fernandez E, Blackman B, Bougie JM, Leister WH, Auld DS, Shen M, Lai K, Boxer MB


Bioorg. Med. Chem. Lett. , (25), 721-7, 2015.

Article Pubmed

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Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.


Brimacombe K, Walsh MJ, Liu L, Vásquez-Valdivieso MG, Morgan HP, McNae I, Fothergill-Gilmore LA, Michels PA, Auld DS, Simeonov A, Walkinshaw MD, Shen M, Boxer MB


ACS Med Chem Lett , (5), 12-7, 2014.

Article Pubmed

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