Program

56
11
4
2
1
1
1
1

Journal Year Published

1
6
1
7
5
6
8
7
6
5
5

Author

57
183
175
144
135
127
119
118
115
108
94
87
81
77
52
50
45
44
42
34

Category

22
18
15
14
7
5
3
1
1

Keyword

32
15
15
13
11
10
10
9
8
8
7
7
7
6
6
6
6
6
5
5

Journal

9
6
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Anti-parasitic Activity.


Davis MI, Patrick S, Blanding WM, Dwivedi V, Suryadi J, Golden JE, Coussens NP, Lee OW, Shen M, Boxer MB, Hall M, Sharlow ER, Drew ME, Morris JC


Antimicrob. Agents Chemother. , 2016.

Article Pubmed

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A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics.


Tschapalda K, Zhang Y, Liu L, Golovnina K, Schlemper T, Eichmann TO, Lal-Nag M, Sreenivasan U, McLenithan J, Ziegler S, Sztalryd C, Lass A, Auld D, Oliver B, Waldmann H, Li Z, Shen M, Boxer MB, Beller M


EBioMedicine , (8), 49-59, 2016.

Article Pubmed

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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.


Pacold ME, et al.


Nat. Chem. Biol. , (12), 452-8, 2016.

Article Pubmed

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Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma.


Satoh K, Zhang L, Zhang Y, Chelluri R, Boufraqech M, Nilubol N, Patel D, Shen M, Kebebew E


Clin. Cancer Res. , (22), 3458-66, 2016.

Article Pubmed

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Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.


Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, Tian Z, Yu Z, Boxer MB, Kiefer JA, Copland JA, Smallridge RC, Li Z, Shen M, Kebebew E


Oncotarget , (6), 9073-85, 2015.

Article Pubmed

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Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.


Ong CC, et al.


Breast Cancer Res. , (17), 59, 2015.

Article Pubmed

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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.


Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe K, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ


Nature , (522), 216-20, 2015.

Article Pubmed

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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.


Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer-Alegre M, Lengyel E


Nat Commun , (6), 6220, 2015.

Article Pubmed

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Structure activity relationships of human galactokinase inhibitors.


Liu L, Tang M, Walsh MJ, Brimacombe K, Pragani R, Tanega C, Rohde JM, Baker H, Fernandez E, Blackman B, Bougie JM, Leister WH, Auld DS, Shen M, Lai K, Boxer MB


Bioorg. Med. Chem. Lett. , (25), 721-7, 2015.

Article Pubmed

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