Program

42
5
1
1
1

Journal Year Published

1
7
2
5
3
7
4
6
1
3
3
1

Author

43
202
181
149
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43

Category

26
12
11
10
2
1
1

Keyword

22
14
9
8
7
6
6
5
5
4
4
4
3
3
3
3
3
3
3
3

Journal

10
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.


Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales S, Mott BT, Rai Bantukallu G, Jansen DJ, Henderson M, Urban DJ, Hall M, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X


Cell Chem Biol , (23), 769-81, 2016.

Article Pubmed

Sample image from publication page

A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies.


Zhang Y, Fox JT, Park YU, Elliott G, Rai Bantukallu G, Cai M, Sakamuru S, Huang R, Xia M, Lee K, Jeon MH, Mathew BP, Park HD, Edelmann W, Park CY, Hong SY, Maloney D, Myung K


Cancer Res. , 2016.

Article Pubmed

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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.


Pacold ME, et al.


Nat. Chem. Biol. , (12), 452-8, 2016.

Article Pubmed

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Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants.


Smith SJ, Pauly GT, Akram A, Melody K, Rai Bantukallu G, Maloney DJ, Ambrose Z, Thomas C, Schneider JT, Hughes SH


Retrovirology , (13), 11, 2016.

Article Pubmed

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KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.


Duan L, Rai Bantukallu G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, Hsieh JT, Liu ZP


Chem. Biol. , (22), 1185-96, 2015.

Article Pubmed

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Discovery of a novel general anesthetic chemotype using high-throughput screening.


McKinstry-Wu AR, Bu W, Rai Bantukallu G, Lea WA, Weiser BP, Liang DF, Simeonov A, Jadhav A, Maloney DJ, Eckenhoff RG


Anesthesiology , (122), 325-33, 2015.

Article Pubmed

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.


Taylor-Fishwick DA, Weaver J, Glenn L, Kuhn N, Rai Bantukallu G, Jadhav A, Simeonov A, Dudda A, Schmoll D, Holman TR, Maloney DJ, Nadler JL


Diabetologia , (58), 549-57, 2015.

Article Pubmed

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Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition.


Gormally MV, Dexheimer TS, Marsico G, Sanders DA, Lowe C, Matak-Vinković D, Michael S, Jadhav A, Rai Bantukallu G, Maloney DJ, Simeonov A, Balasubramanian S


Nat Commun , (5), 5165, 2014.

Article Pubmed

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Biochemical assays for the discovery of TDP1 inhibitors.


Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai Bantukallu G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, Simeonov A, Pommier Y


Mol. Cancer Ther. , (13), 2116-26, 2014.

Article Pubmed

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