Program

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Journal Year Published

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Author

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134
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125
118
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114
108
88
86
81
73
56
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43
43
42
34

Category

12
8
6
4
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Keyword

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5
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Journal

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NCATS Publications

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.


Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe K, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ


Nature , (522), 216-20, 2015.

Article Pubmed

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Structure activity relationships of human galactokinase inhibitors.


Liu L, Tang M, Walsh MJ, Brimacombe K, Pragani R, Tanega C, Rohde JM, Baker H, Fernandez E, Blackman B, Bougie JM, Leister WH, Auld DS, Shen M, Lai K, Boxer MB


Bioorg. Med. Chem. Lett. , (25), 721-7, 2015.

Article Pubmed

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Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.


Brimacombe K, Walsh MJ, Liu L, Vásquez-Valdivieso MG, Morgan HP, McNae I, Fothergill-Gilmore LA, Michels PA, Auld DS, Simeonov A, Walkinshaw MD, Shen M, Boxer MB


ACS Med Chem Lett , (5), 12-7, 2014.

Article Pubmed

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Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.


Blackford JA, Brimacombe K, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin C, Simons SS


Mol. Endocrinol. , (28), 1194-206, 2014.

Article Pubmed

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Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor.


Patnaik S, Marugan J, Liu K, Zheng W, Southall N, Dehdashti SJ, Thorsell A, Heilig M, Bell L, Zook M, Eskay B, Brimacombe K, Austin C


J. Med. Chem. , (56), 9045-56, 2013.

Article Pubmed

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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.


Anastasiou D, et al.


Nat. Chem. Biol. , (8), 839-47, 2012.

Article Pubmed

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2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Walsh MJ, Brimacombe K, Veith H, Bougie JM, Daniel T, Leister W, Cantley LC, Israelsen WJ, Vander Heiden MG, Shen M, Auld DS, Thomas C, Boxer MB


Bioorg. Med. Chem. Lett. , (21), 6322-7, 2011.

Article Pubmed

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