Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

53
74
112
103
189
334
339
388
128
66
52
51
37
20
10
4
5
6
3
3

Author

201
181
149
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1270
612
563
415
347
304
212
208
160
146
130
122
112
111
100
99
91
83
82
82

Journal

55
55
46
31
30
28
21
19
18
17
17
17
17
17
16
16
16
15
14
13

NCATS Publications

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.


Davis RE, et al.


Nature , (463), 88-92, 2010.

Article Pubmed

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Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Boxer MB, Jiang J, Vander Heiden MG, Shen M, Skoumbourdis AP, Southall N, Veith H, Leister W, Austin C, Park HW, Inglese J, Cantley LC, Auld DS, Thomas C


J. Med. Chem. , (53), 1048-55, 2010.

Article Pubmed

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Identification of small molecule compounds that inhibit the HIF-1 signaling pathway.


Xia M, Bi K, Huang R, Cho MH, Sakamuru S, Miller SC, Li H, Sun Y, Printen J, Austin C, Inglese J


Mol. Cancer , (8), 117, 2009.

Article Pubmed

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Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.


Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin C, Thomas C, Shoichet BK, Maloney DJ


J. Med. Chem. , (53), 52-60, 2010.

Article Pubmed

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A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.


Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin C, Oppermann U, Simeonov A


Nucleic Acids Res. , (38), e11, 2010.

Article Pubmed

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Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.


Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J


J. Med. Chem. , (52), 7950-3, 2009.

Article Pubmed

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Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.


Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin C, Lloyd DG, Auld DS


Nat. Biotechnol. , (27), 1050-5, 2009.

Article Pubmed

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