Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

53
74
112
103
189
334
339
388
128
66
52
51
37
20
10
4
5
6
3
3

Author

201
181
149
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1270
612
563
415
347
304
212
208
160
146
130
122
112
111
100
99
91
83
82
82

Journal

55
55
46
31
30
28
21
19
18
17
17
17
17
17
16
16
16
15
14
13

NCATS Publications

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.


Yoon HY, Kales S, Luo R, Lipkowitz S, Randazzo PA


Biol. Cell , (103), 171-84, 2011.

Article Pubmed

Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay.


Prast-Nielsen S, Dexheimer TS, Schultz L, Stafford WC, Cheng Q, Xu J, Jadhav A, Arnér ES, Simeonov A


Free Radic. Biol. Med. , (50), 1114-23, 2011.

Article Pubmed

Sample image from publication page

Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.


Marugan J, Zheng W, Motabar O, Southall N, Goldin E, Westbroek W, Stubblefield BK, Sidransky E, Aungst RA, Lea WA, Simeonov A, Leister W, Austin C


J. Med. Chem. , (54), 1033-58, 2011.

Article Pubmed

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Cooperative epigenetic modulation by cancer amplicon genes.


Rui L, et al.


Cancer Cell , (18), 590-605, 2010.

Article Pubmed

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Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.


King ON, Li XS, Sakurai M, Kawamura A, Rose NR, Ng SS, Quinn AM, Rai Bantukallu G, Mott BT, Beswick P, Klose RJ, Oppermann U, Jadhav A, Heightman TD, Maloney DJ, Schofield CJ, Simeonov A


PLoS ONE , (5), e15535, 2010.

Article Pubmed

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A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.


Neumann S, Eliseeva E, McCoy JG, Napolitano G, Giuliani C, Monaco F, Huang W, Gershengorn MC


J. Clin. Endocrinol. Metab. , (96), 548-54, 2011.

Article Pubmed

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CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP.


Ju W, Zhang M, Jiang J, Thomas C, Oh U, Bryant BR, Chen J, Sato N, Tagaya Y, Morris JC, Janik JE, Jacobson S, Waldmann TA


Blood , (117), 1938-46, 2011.

Article Pubmed

Sample image from publication page