Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

4
55
111
103
188
334
338
388
128
65
52
51
37
19
10
2
4
3
5
3

Author

185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1257
606
556
411
341
300
210
208
160
146
127
122
112
111
100
97
91
83
82
82

Journal

53
51
46
30
28
28
21
18
17
17
16
16
16
16
15
14
14
14
14
13

NCATS Publications

Identification of small molecule compounds that inhibit the HIF-1 signaling pathway.


Xia M, Bi K, Huang R, Cho MH, Sakamuru S, Miller SC, Li H, Sun Y, Printen J, Austin C, Inglese J


Mol. Cancer , (8), 117, 2009.

Article Pubmed

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Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.


Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin C, Thomas C, Shoichet BK, Maloney DJ


J. Med. Chem. , (53), 52-60, 2010.

Article Pubmed

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A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.


Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin C, Oppermann U, Simeonov A


Nucleic Acids Res. , (38), e11, 2010.

Article Pubmed

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Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.


Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J


J. Med. Chem. , (52), 7950-3, 2009.

Article Pubmed

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Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.


Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin C, Lloyd DG, Auld DS


Nat. Biotechnol. , (27), 1050-5, 2009.

Article Pubmed

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Multi-gram scale synthesis of FR180204.


Patnaik S, Dietz HC, Zheng W, Austin C, Marugan J


J. Org. Chem. , (74), 8870-3, 2009.

Article Pubmed

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Breaking the hierarchy--a new cluster selection mechanism for hierarchical clustering methods.


Zahoránszky LA, Katona GY, Hári P, Málnási-Csizmadia A, Zweig KA, Zahoranszky-Kohalmi G


Algorithms Mol Biol , (4), 12, 2009.

Article Pubmed