Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

60
76
112
105
189
334
339
388
128
67
52
51
37
22
10
4
5
6
3
3

Author

202
181
149
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1275
615
567
418
347
304
212
208
160
146
130
122
112
111
100
99
91
83
82
82

Journal

55
55
46
31
30
28
21
19
18
17
17
17
17
17
16
16
16
15
14
13

NCATS Publications

Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.


Kenyon V, Rai Bantukallu G, Jadhav A, Schultz L, Armstrong M, Jameson JB, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR


J. Med. Chem. , (54), 5485-97, 2011.

Article Pubmed

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The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site.


Morgan HP, McNae IW, Nowicki MW, Zhong W, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD


J. Biol. Chem. , (286), 31232-40, 2011.

Article Pubmed

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Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.


Hall M, Brimacombe K, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, Fales HM, Gottesman MM


J. Med. Chem. , (54), 5878-89, 2011.

Article Pubmed

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Adolescent BMI and risk of diabetes versus coronary disease.


Cure Ramirez P, Cure-Cure C


N. Engl. J. Med. , (364), 2558-9; author reply 2559, 2011.

Article Pubmed

Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity.


Peterson KE, Cinelli MA, Morrell AE, Mehta A, Dexheimer TS, Agama K, Antony S, Pommier Y, Cushman M


J. Med. Chem. , (54), 4937-53, 2011.

Article Pubmed

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Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells.


Leister KP, Huang R, Goodwin BL, Chen A, Austin C, Xia M


Curr Chem Genomics , (5), 21-9, 2011.

Article Pubmed

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Exploratory analysis of kinetic solubility measurements of a small molecule library.


Guha R, Dexheimer TS, Kestranek AN, Jadhav A, Chervenak AM, Ford MG, Simeonov A, Roth GP, Thomas C


Bioorg. Med. Chem. , (19), 4127-34, 2011.

Article Pubmed

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Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.


Sooryakumar D, Dexheimer TS, Teicher BA, Pommier Y


Mol. Cancer Ther. , (10), 1490-9, 2011.

Article Pubmed

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