Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

53
74
112
103
189
334
339
388
128
66
52
51
37
20
10
4
5
6
3
3

Author

201
181
149
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1270
612
563
415
347
304
212
208
160
146
130
122
112
111
100
99
91
83
82
82

Journal

55
55
46
31
30
28
21
19
18
17
17
17
17
17
16
16
16
15
14
13

NCATS Publications

Down syndrome: national conference on patient registries, research databases, and biobanks.


Oster-Granite ML, Parisi MA, Abbeduto L, Berlin DS, Bodine C, Bynum D, Capone G, Collier E, Hall D, Kaeser L, Kaufmann P, Krischer J, Livingston M, McCabe LL, Pace J, Pfenninger K, Rasmussen SA, Reeves RH, Rubinstein Y, Sherman S, Terry SF, Whitten MS, Williams S, McCabe ER, Maddox YT


Mol. Genet. Metab. , (104), 13-22, .

Article Pubmed

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RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors.


Martin SE, Wu ZH, Gehlhaus K, Jones R, Zhang YW, Guha R, Miyamoto S, Pommier Y, Caplen NJ


Curr Cancer Drug Targets , (11), 976-86, 2011.

Pubmed

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7-azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents.


Kiselev E, DeGuire S, Morrell A, Agama K, Dexheimer TS, Pommier Y, Cushman M


J. Med. Chem. , (54), 6106-16, 2011.

Article Pubmed

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Discovery, synthesis, and biological evaluation of novel SMN protein modulators.


Xiao J, Marugan J, Zheng W, Titus S, Southall N, Cherry JJ, Evans M, Androphy EJ, Austin C


J. Med. Chem. , (54), 6215-33, 2011.

Article Pubmed

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Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.


Yuan J, Cheng KC, Johnson RL, Huang R, Pattaradilokrat S, Liu A, Guha R, Fidock DA, Inglese J, Wellems TE, Austin C, Su XZ


Science , (333), 724-9, 2011.

Article Pubmed

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Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.


Kenyon V, Rai Bantukallu G, Jadhav A, Schultz L, Armstrong M, Jameson JB, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR


J. Med. Chem. , (54), 5485-97, 2011.

Article Pubmed

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The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site.


Morgan HP, McNae IW, Nowicki MW, Zhong W, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD


J. Biol. Chem. , (286), 31232-40, 2011.

Article Pubmed

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Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.


Hall M, Brimacombe K, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, Fales HM, Gottesman MM


J. Med. Chem. , (54), 5878-89, 2011.

Article Pubmed

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