Program

769
585
107
103
99
36
26
22
16
11
10
10
9
4
3

Journal Year Published

27
106
99
178
329
335
384
122
64
50
50
36
18
9
4
3
4
3
2
2

Author

183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1226
594
541
387
337
299
210
196
160
145
123
122
110
108
98
97
91
83
82
81

Journal

50
49
43
28
28
24
21
18
16
16
16
15
15
15
14
14
14
14
14
13

NCATS Publications

Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase.


Shi ZD, Motabar O, Goldin E, Liu K, Southall N, Sidransky E, Austin C, Griffiths GL, Zheng W


Anal Bioanal Chem , (394), 1903-9, 2009.

Article Pubmed

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Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.


Shukla SJ, Nguyen T, Macarthur R, Simeonov A, Frazee WJ, Hallis TM, Marks BD, Singh U, Eliason HC, Printen J, Austin C, Inglese J, Auld DS


Assay Drug Dev Technol , (7), 143-69, 2009.

Article Pubmed

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Identification of chemical compounds that induce HIF-1alpha activity.


Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin C


Toxicol. Sci. , (112), 153-63, 2009.

Article Pubmed

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Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.


Cronin KD, Ge D, Manninger P, Linnertz C, Rossoshek A, Orrison BM, Bernard DJ, El-Agnaf OM, Schlossmacher MG, Nussbaum RL, Chiba-Falek O


Hum. Mol. Genet. , (18), 3274-85, 2009.

Article Pubmed

Monitoring compound integrity with cytochrome P450 assays and qHTS.


MacArthur R, Leister W, Veith H, Shinn P, Southall N, Austin C, Inglese J, Auld DS


J Biomol Screen , (14), 538-46, 2009.

Article Pubmed

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Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.


Skoumbourdis AP, LeClair C, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin C, Michnick SW, Xia M, Thomas C


Bioorg. Med. Chem. Lett. , (19), 3686-92, 2009.

Article Pubmed

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A new resorufin-based alpha-glucosidase assay for high-throughput screening.


Motabar O, Shi ZD, Goldin E, Liu K, Southall N, Sidransky E, Austin C, Griffiths GL, Zheng W


Anal. Biochem. , (390), 79-84, 2009.

Article Pubmed

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Imaging protein-protein interactions by Förster resonance energy transfer (FRET) microscopy in live cells.


Brzostowski JA, Meckel T, Hong J, Chen A, Jin T


Curr Protoc Protein Sci , (Chapter 19), Unit19.5, 2009.

Article Pubmed