Program

769
585
107
103
99
36
26
22
16
11
10
10
9
4
3

Journal Year Published

27
106
99
178
329
337
385
123
65
50
51
36
18
9
2
4
3
5
3
2

Author

183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1226
594
541
387
337
299
210
196
160
145
123
122
110
108
98
97
91
83
82
81

Journal

50
49
43
28
28
24
21
18
16
16
16
15
15
15
14
14
14
14
14
13

NCATS Publications

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Boxer MB, Jiang J, Vander Heiden MG, Shen M, Skoumbourdis AP, Southall N, Veith H, Leister W, Austin C, Park HW, Inglese J, Cantley LC, Auld DS, Thomas C


J. Med. Chem. , (53), 1048-55, 2010.

Article Pubmed

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Identification of small molecule compounds that inhibit the HIF-1 signaling pathway.


Xia M, Bi K, Huang R, Cho MH, Sakamuru S, Miller SC, Li H, Sun Y, Printen J, Austin C, Inglese J


Mol. Cancer , (8), 117, 2009.

Article Pubmed

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Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.


Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin C, Thomas C, Shoichet BK, Maloney DJ


J. Med. Chem. , (53), 52-60, 2010.

Article Pubmed

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A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.


Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin C, Oppermann U, Simeonov A


Nucleic Acids Res. , (38), e11, 2010.

Article Pubmed

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Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.


Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J


J. Med. Chem. , (52), 7950-3, 2009.

Article Pubmed

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Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.


Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin C, Lloyd DG, Auld DS


Nat. Biotechnol. , (27), 1050-5, 2009.

Article Pubmed

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Multi-gram scale synthesis of FR180204.


Patnaik S, Dietz HC, Zheng W, Austin C, Marugan J


J. Org. Chem. , (74), 8870-3, 2009.

Article Pubmed

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