Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

4
55
111
103
188
334
338
388
128
65
52
51
37
20
10
4
5
6
3
3

Author

185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1262
610
560
411
345
302
210
208
160
146
129
122
112
111
100
97
91
83
82
82

Journal

53
51
46
30
28
28
21
19
18
17
17
16
16
16
16
15
14
14
14
13

NCATS Publications

Biology-driven library design for probe discovery.


Inglese J, Hasson SA


Chem. Biol. , (18), 1204-5, 2011.

Article Pubmed

A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide.


Motabar O, Goldin E, Leister W, Liu K, Southall N, Huang W, Marugan J, Sidransky E, Zheng W


Anal Bioanal Chem , (402), 731-9, 2012.

Article Pubmed

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Open Data, Open Source and Open Standards in chemistry: The Blue Obelisk five years on.


O'Boyle NM, Guha R, Willighagen EL, Adams SE, Alvarsson J, Bradley JC, Filippov IV, Hanson RM, Hanwell MD, Hutchison GR, James CA, Jeliazkova N, Lang AS, Langner KM, Lonie DC, Lowe DM, Pansanel J, Pavlov D, Spjuth O, Steinbeck C, Tenderholt AL, Theisen KJ, Murray-Rust P


J Cheminform , (3), 37, 2011.

Article Pubmed

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Parsimonious discovery of synergistic drug combinations.


Severyn B, Liehr RA, Wolicki A, Nguyen KH, Hudak EM, Ferrer-Alegre M, Caldwell JS, Hermes JD, Li J, Tudor M


ACS Chem. Biol. , (6), 1391-8, 2011.

Article Pubmed

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2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Walsh MJ, Brimacombe K, Veith H, Bougie JM, Daniel T, Leister W, Cantley LC, Israelsen WJ, Vander Heiden MG, Shen M, Auld DS, Thomas C, Boxer MB


Bioorg. Med. Chem. Lett. , (21), 6322-7, 2011.

Article Pubmed

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Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.


Naidu MD, Agarwal R, Pena LA, Cunha L, Mezei M, Shen M, Wilson DM, Liu Y, Sanchez Z, Chaudhary P, Wilson SH, Waring MJ


PLoS ONE , (6), e23679, 2011.

Article Pubmed

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Down syndrome: national conference on patient registries, research databases, and biobanks.


Oster-Granite ML, Parisi MA, Abbeduto L, Berlin DS, Bodine C, Bynum D, Capone G, Collier E, Hall D, Kaeser L, Kaufmann P, Krischer J, Livingston M, McCabe LL, Pace J, Pfenninger K, Rasmussen SA, Reeves RH, Rubinstein Y, Sherman S, Terry SF, Whitten MS, Williams S, McCabe ER, Maddox YT


Mol. Genet. Metab. , (104), 13-22, .

Article Pubmed

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RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors.


Martin SE, Wu ZH, Gehlhaus K, Jones R, Zhang YW, Guha R, Miyamoto S, Pommier Y, Caplen NJ


Curr Cancer Drug Targets , (11), 976-86, 2011.

Pubmed

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