Program

769
585
109
107
103
36
26
22
16
11
10
10
9
4
3
1

Journal Year Published

4
55
111
103
188
334
338
388
128
65
52
51
37
20
10
4
5
6
3
3

Author

185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

377
362
314
112
86
72
21
20
19
19
3
2

Keyword

1262
610
560
411
345
302
210
208
160
146
129
122
112
111
100
97
91
83
82
82

Journal

53
51
46
30
28
28
21
19
18
17
17
16
16
16
16
15
14
14
14
13

NCATS Publications

Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.


Cruz PG, Auld DS, Schultz PJ, Lovell S, Battaile KP, MacArthur R, Shen M, Tamayo-Castillo G, Inglese J, Sherman DH


Chem. Biol. , (18), 1442-52, 2011.

Article Pubmed

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Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells.


Chen J, Dexheimer TS, Ai Y, Liang Q, Villamil MA, Inglese J, Maloney DJ, Jadhav A, Simeonov A, Zhuang Z


Chem. Biol. , (18), 1390-400, 2011.

Article Pubmed

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Separation of Betti Reaction Product Enantiomers: Absolute Configuration and Inhibition of Botulinum Neurotoxin A.


Cardellina JH, Vieira RC, Eccard V, Skerry J, Montgomery V, Campbell Y, Roxas-Duncan V, Leister W, LeClair C, Maloney DJ, Padula D, Pescitelli G, Khavrutskii I, Hu X, Wallqvist A, Smith LA


ACS Med Chem Lett , (2), 396-401, 2011.

Article Pubmed

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Natural history of MELAS associated with mitochondrial DNA m.3243A>G genotype.


Kaufmann P, Engelstad K, Wei Y, Kulikova R, Oskoui M, Sproule DM, Battista V, Koenigsberger DY, Pascual JM, Shanske S, Sano M, Mao X, Hirano M, Shungu DC, Dimauro S, De Vivo DC


Neurology , (77), 1965-71, 2011.

Article Pubmed

Common seed analysis to identify off-target effects in siRNA screens.


Marine S, Bahl A, Ferrer-Alegre M, Buehler E


J Biomol Screen , (17), 370-8, 2012.

Article Pubmed

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Classification of scaffold-hopping approaches.


Sun H, Tawa G, Wallqvist A


Drug Discov. Today , (17), 310-24, 2012.

Article Pubmed

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.


Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang J, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas C, Vander Heiden MG, Cantley LC


Science , (334), 1278-83, 2011.

Article Pubmed

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Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3.


Tang LY, Yamashita M, Coussens NP, Tang Y, Wang X, Li C, Deng CX, Cheng SY, Zhang YE


EMBO J. , (30), 4777-89, 2011.

Article Pubmed

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Comprehensive analysis of kinase inhibitor selectivity.


Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP


Nat. Biotechnol. , (29), 1046-51, 2011.

Article Pubmed

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