Program

585
109
107
103
36
3
769
26
22
16
11
10
10
9
4
1

Journal Year Published

31
94
73
129
80
82
75
65
51
40
40
29
14
4
3
2

Author

183
155
142
134
127
118
118
114
108
93
86
81
71
57
52
50
43
43
42
34

Category

340
309
283
84
69
49
21
19
12
9
3
2

Keyword

367
212
114
112
88
79
74
70
66
59
54
53
46
45
40
40
37
36
35
35

Journal

48
37
30
28
25
24
20
16
14
14
14
13
12
11
10
10
9
9
9
8

NCATS Publications

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma.


Chan K, Robert F, Oertlin C, Kapeller-Libermann D, Avizonis D, Gutierrez J, Handly-Santana A, Doubrovin M, Park J, Schoepfer C, Da Silva B, Yao M, Gorton F, Shi J, Thomas C, Brown LE, Porco JA, Pollak M, Larsson O, Pelletier J, Chio IIC


Nat Commun , (10), 5151, 2019.

Article Pubmed

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Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.


Kaur S, Schwartz AL, Jordan DG, Soto-Pantoja DR, Kuo B, Elkahloun AG, Mathews Griner L, Thomas C, Ferrer-Alegre M, Thomas A, Tang SW, Rajapakse VN, Pommier Y, Roberts DD


Front Oncol , (9), 994, 2019.

Article Pubmed

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High-potency ligands for DREADD imaging and activation in rodents and monkeys.


Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris P, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M


Nat Commun , (10), 4627, 2019.

Article Pubmed

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Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets.


Vootukuri S, Li J, Nedelman M, Thomas C, Jiang J, Babayeva M, Coller BS


J Clin Transl Sci , (3), 65-74, 2019.

Article Pubmed

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Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode.


Whitehouse AJ, Libardo MDJ, Kasbekar M, Brear PD, Fischer G, Thomas C, Barry CE, Boshoff HIM, Coyne AG, Abell C


J. Med. Chem. , 2019.

Article Pubmed

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High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.


Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer-Alegre M, Grant N, Thomas C, Schlegel R, Yuan H


Papillomavirus Res , (8), 100181, 2019.

Article Pubmed

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Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.


Bian Y, Teper Y, Mathews Griner LA, Aiken TJ, Shukla V, Guha R, Shinn P, Xin HW, Pflicke H, Powers AS, Li D, Jiang J, Patel P, Rogers SA, Aubé J, Ferrer-Alegre M, Thomas C, Rudloff U


Mol. Cancer Ther. , (18), 2097-2110, 2019.

Article Pubmed

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(R)-Ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anaesthetic doses.


Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris P, Stewart BW, Thomas C, Thompson SM, Moaddel R, Gould TD


Br. J. Pharmacol. , (176), 2573-2592, 2019.

Article Pubmed

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