Program

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14
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1

Journal Year Published

3
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3
3
2
2
4
4
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3

Author

26
185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

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12
7
1
1
1
1

Keyword

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12
11
7
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6
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4
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3

Journal

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3
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1

NCATS Publications

Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets.


Vootukuri S, Li J, Nedelman M, Thomas C, Jiang J, Babayeva M, Coller BS


J Clin Transl Sci , (3), 65-74, 2019.

Article Pubmed

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Overcoming adaptive therapy resistance in AML by targeting immune response pathways.


Melgar K, Walker MM, Jones LM, Bolanos LC, Hueneman K, Wunderlich M, Jiang J, Wilson K, Zhang X, Sutter P, Wang A, Xu X, Choi K, Tawa G, Lorimer D, Abendroth J, O'Brien E, Hoyt S, Berman E, Famulare CA, Mulloy JC, Levine RL, Perentesis JP, Thomas C, Starczynowski DT


Sci Transl Med , (11), 2019.

Article Pubmed

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Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.


Bian Y, Teper Y, Mathews Griner LA, Aiken TJ, Shukla V, Guha R, Shinn P, Xin HW, Pflicke H, Powers AS, Li D, Jiang J, Patel P, Rogers SA, Aubé J, Ferrer-Alegre M, Thomas C, Rudloff U


Mol. Cancer Ther. , (18), 2097-2110, 2019.

Article Pubmed

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ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells.


Wang S, Chen XA, Hu J, Jiang J, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y


Mol. Cancer Ther. , (14), 877-88, 2015.

Article Pubmed

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Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.


Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R, Johnston DG, Jiang J, Jiang J, Israelsen WJ, Keane J, Thomas C, Clish C, Vander Heiden M, Vanden Heiden M, Xavier RJ, O'Neill LA


Cell Metab. , (21), 65-80, 2015.

Article Pubmed

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Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity.


Lu G, Lomonosova E, Cheng X, Moran EA, Meyers MJ, Le Grice SF, Thomas C, Jiang J, Meck C, Hirsch DR, D'Erasmo MP, Suyabatmaz DM, Murelli RP, Tavis JE


Antimicrob. Agents Chemother. , (59), 1070-9, 2015.

Article Pubmed

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RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.


Li J, Vootukuri S, Shang Y, Negri A, Jiang J, Nedelman M, Diacovo TG, Filizola M, Thomas C, Coller BS


Arterioscler. Thromb. Vasc. Biol. , (34), 2321-9, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.


Jiang J, McCoy JG, Shen M, LeClair C, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas C


Bioorg. Med. Chem. Lett. , (24), 1148-53, 2014.

Article Pubmed

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