Program

9

Journal Year Published

6
6
3
1
1
1

Author

18
212
185
156
149
137
135
129
127
108
107
96
83
79
70
70
63
53
50
46
46

Category

6
6
3
1

Keyword

3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

Journal

4
3
2
2
1
1
1
1
1
1
1

NCATS Publications

The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.


Gorshkov K, Chen C, Bostwick R, Rasmussen L, Tran BN, Cheng Y, Xu M, Pradhan M, Henderson M, Zhu W, Oh E, Susumu K, Wolak M, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Carlos de la Torre J, Simeonov A, Michael S, Hall M, Lo D, Zheng W


ACS Infect Dis , 2020.

Article Pubmed

Sample image from publication page

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.




J Med Chem , (63), 10984-11011, 2020.

Article Pubmed

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Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays.


Crowe A, Henderson M, Anderson J, Titus SA, Zakharov A, Simeonov A, Buist A, Delay C, Moechars D, Trojanowski JQ, Lee VM, Brunden KR


J. Biol. Chem. , (295), 4001-4013, 2020.

Article Pubmed

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Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.


Kearney SE, et al.


ACS Cent Sci , (4), 1727-1741, 2018.

Article Pubmed

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Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.


Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

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KDM5 histone demethylases repress immune response via suppression of STING.


Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai Bantukallu G, Kales S, Henderson M, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall M, Cheng X, Shadel GS, Yan Q


PLoS Biol. , (16), e2006134, 2018.

Article Pubmed

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