Program

84
25
4
3
1
1
1

Journal Year Published

7
17
12
19
13
8
7
8
2
1

Author

94
183
175
144
135
127
119
118
115
108
87
81
77
57
52
50
45
44
42
34

Category

57
31
27
7
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening.


Lin GL, et al.


Sci Transl Med , (11), 2019.

Article Pubmed

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Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.


Kaur S, Schwartz AL, Jordan DG, Soto-Pantoja DR, Kuo B, Elkahloun AG, Mathews Griner L, Thomas C, Ferrer-Alegre M, Thomas A, Tang SW, Rajapakse VN, Pommier Y, Roberts DD


Front Oncol , (9), 994, 2019.

Article Pubmed

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High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.


Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer-Alegre M, Grant N, Thomas C, Schlegel R, Yuan H


Papillomavirus Res , (8), 100181, 2019.

Article Pubmed

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Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.


Bian Y, Teper Y, Mathews Griner LA, Aiken TJ, Shukla V, Guha R, Shinn P, Xin HW, Pflicke H, Powers AS, Li D, Jiang J, Patel P, Rogers SA, Aubé J, Ferrer-Alegre M, Thomas C, Rudloff U


Mol. Cancer Ther. , (18), 2097-2110, 2019.

Article Pubmed

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Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists.


Patnaik S, Basu D, Southall N, Dehdashti S, Wan K, Zheng W, Ferrer-Alegre M, Taylor M, Engel DA, Marugan JJ


Bioorg. Med. Chem. Lett. , (29), 1113-1119, 2019.

Article Pubmed

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Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.


Fontelonga TM, Jordan B, Nunes AM, Barraza-Flores P, Bolden N, Wuebbles RD, Griner LM, Hu X, Ferrer-Alegre M, Marugan J, Southall N, Burkin DJ


Hum. Mol. Genet. , (28), 2120-2132, 2019.

Article Pubmed

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A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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