Program

82
22
4
3
1
1

Journal Year Published

1
17
12
19
13
8
7
8
2
1

Author

88
182
174
134
134
125
118
116
114
108
86
81
73
56
51
50
43
43
42
34

Category

56
31
27
6
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

Sample image from publication page

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.


Wilson K, Mathews-Griner LA, Williamson T, Guha R, Chen L, Shinn P, McKnight C, Michael S, Klumpp-Thomas C, Binder ZA, Ferrer-Alegre M, Gallia GL, Thomas C, Riggins GJ


SLAS Technol , 2472630318803749, 2018.

Article Pubmed

Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.


Luderman KD, Conroy JL, Free RB, Southall N, Ferrer-Alegre M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aubé J, Lane JR, Frankowski KJ, Sibley DR


Mol. Pharmacol. , (94), 1197-1209, 2018.

Article Pubmed

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Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy.


Feliz-Mosquea YR, Christensen AA, Wilson AS, Westwood B, Varagic J, Meléndez GC, Schwartz AL, Chen QR, Mathews Griner L, Guha R, Thomas C, Ferrer-Alegre M, Merino MJ, Cook KL, Roberts DD, Soto-Pantoja DR


Breast Cancer Res. Treat. , (172), 69-82, 2018.

Article Pubmed