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Author

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Keyword

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Journal

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NCATS Publications

A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.


Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang A, Xu X, Dulcey AE, Marugan J, Ferrer-Alegre M, Arav-Boger R


PLoS Pathog. , (12), e1005717, 2016.

Article Pubmed

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Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.


Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer-Alegre M, Javitch JA, Beuming T, Shi L, Southall N, Marugan J, Sibley DR


Mol. Pharmacol. , (86), 96-105, 2014.

Article Pubmed

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Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.


Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer-Alegre M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R


J. Biol. Chem. , (289), 16349-61, 2014.

Article Pubmed

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