Program

33
3
1

Journal Year Published

5
1
4
3
4
1
7
3
1
1
3
4
1
2

Author

40
212
185
156
149
137
135
129
127
108
107
96
83
79
70
70
63
53
50
46
46

Category

20
14
10
5
2
1
1
1

Keyword

14
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
2

Journal

6
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.


Abrams RPM, Yasgar A, Teramoto T, Lee MH, Dorjsuren D, Eastman R, Malik N, Zakharov A, Li W, Bachani M, Brimacombe K, Steiner JP, Hall M, Balasubramanian A, Jadhav A, Padmanabhan R, Simeonov A, Nath A


Proc Natl Acad Sci U S A , (117), 31365-31375, 2020.

Article Pubmed

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The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.


Richard AM, Huang R, Waidyanatha S, Shinn P, Collins BJ, Thillainadarajah I, Grulke CM, Williams AJ, Lougee RR, Judson RS, Houck KA, Shobair M, Yang C, Rathman JF, Yasgar A, Fitzpatrick SC, Simeonov A, Thomas RS, Crofton KM, Paules RS, Bucher JR, Austin C, Kavlock RJ, Tice RR


Chem Res Toxicol , 2020.

Article Pubmed

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Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors.


Manz TD, Sivakumaren SC, Ferguson FM, Zhang T, Yasgar A, Seo HS, Ficarro SB, Card JD, Shim H, Miduturu CV, Simeonov A, Shen M, Marto JA, Dhe-Paganon S, Hall M, Cantley LC, Gray NS


J. Med. Chem. , (63), 4880-4895, 2020.

Article Pubmed

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Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors.


Manz TD, Sivakumaren SC, Yasgar A, Hall M, Davis MI, Seo HS, Card JD, Ficarro SB, Shim H, Marto JA, Dhe-Paganon S, Sasaki AT, Boxer MB, Simeonov A, Cantley LC, Shen M, Zhang T, Ferguson FM, Gray NS


ACS Med Chem Lett , (11), 346-352, 2020.

Article Pubmed

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Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.


Kearney SE, et al.


ACS Cent Sci , (4), 1727-1741, 2018.

Article Pubmed

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Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

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