Program

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3

Journal Year Published

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2

Author

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108
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56
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34

Category

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Keyword

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Journal

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NCATS Publications

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.




Cell Discov , (4), 31, 2018.

Article Pubmed

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Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.


Capuzzi SJ, Sun W, Muratov EN, Martínez-Romero C, He S, Zhu W, Li H, Tawa G, Fisher EG, Xu M, Shinn P, Qiu X, García-Sastre A, Zheng W, Tropsha A


J. Med. Chem. , (61), 3582-3594, 2018.

Article Pubmed

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Synergistic drug combination effectively blocks Ebola virus infection.


Sun W, He S, Martínez-Romero C, Kouznetsova J, Tawa G, Xu M, Shinn P, Fisher EG, Long Y, Motabar O, Yang S, Sanderson P, Williamson PR, García-Sastre A, Qiu X, Zheng W


Antiviral Res. , (137), 165-172, 2017.

Article Pubmed

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Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.


Zhang F, Hammack C, Ogden SC, Cheng Y, Lee E, Wen Z, Qian X, Nguyen HN, Li Y, Yao B, Xu M, Xu T, Chen L, Wang Z, Feng H, Huang W, Yoon KJ, Shan C, Huang L, Qin Z, Christian KM, Shi PY, Xu M, Xia M, Zheng W, Wu H, Song H, Tang H, Ming GL, Jin P


Nucleic Acids Res. , (44), 8610-8620, 2016.

Article Pubmed

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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.


Xu M, Lee E, Wen Z, Cheng Y, Huang W, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael S, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H


Nat. Med. , (22), 1101-1107, 2016.

Article Pubmed

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