Program

17
4
2
2

Journal Year Published

1
8
5
7
2
2

Author

25
185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

20
5
2
1
1

Keyword

5
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1

Journal

4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Overcoming adaptive therapy resistance in AML by targeting immune response pathways.


Melgar K, Walker MM, Jones LM, Bolanos LC, Hueneman K, Wunderlich M, Jiang J, Wilson K, Zhang X, Sutter P, Wang A, Xu X, Choi K, Tawa G, Lorimer D, Abendroth J, O'Brien E, Hoyt S, Berman E, Famulare CA, Mulloy JC, Levine RL, Perentesis JP, Thomas C, Starczynowski DT


Sci Transl Med , (11), 2019.

Article Pubmed

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Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.


Highland JN, Morris P, Zanos P, Lovett J, Ghosh S, Wang A, Zarate CA, Thomas C, Moaddel R, Gould TD


J. Psychopharmacol. (Oxford) , 269881118812095, 2018.

Article Pubmed

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Discovery and lead identification of quinazoline-based BRD4 inhibitors.


Yang SM, Urban DJ, Yoshioka M, Strovel JW, Fletcher S, Wang A, Xu X, Shah P, Hu X, Hall M, Jadhav A, Maloney DJ


Bioorg. Med. Chem. Lett. , (28), 3483-3488, 2018.

Article Pubmed

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In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy.


Wiederhold NP, Xu X, Wang A, Najvar LK, Garvey EP, Ottinger E, Alimardanov A, Cradock J, Behnke M, Hoekstra WJ, Brand SR, Schotzinger RJ, Jaramillo R, Olivo M, Kirkpatrick WR, Patterson TF


Antimicrob. Agents Chemother. , 2018.

Article Pubmed

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

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Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.


Rolt A, Le D, Hu Z, Wang A, Shah P, Singleton M, Hughes E, Dulcey AE, He S, Imamura M, Uchida T, Chayama K, Xu X, Marugan J, Liang TJ


J. Infect. Dis. , 2018.

Article Pubmed

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban DJ, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

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