Program

14

Journal Year Published

3
2
4
2
1
2

Author

14
182
174
134
134
125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

9
4
2
1
1
1

Keyword

3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Journal

3
2
2
1
1
1
1
1
1
1

NCATS Publications

Glypican-3 Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.


Fu Y, Urban D, Nani RR, Zhang YF, Li N, Fu H, Shah H, Gorka AP, Guha R, Chen L, Hall M, Schnermann MJ, Ho M


Hepatology , 2018.

Article Pubmed

Discovery and lead identification of quinazoline-based BRD4 inhibitors.


Yang SM, Urban D, Yoshioka M, Strovel JW, Fletcher S, Wang A, Xu X, Shah P, Hu X, Hall M, Jadhav A, Maloney DJ


Bioorg. Med. Chem. Lett. , (28), 3483-3488, 2018.

Article Pubmed

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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).


Rai Bantukallu G, Brimacombe K, Mott BT, Urban D, Hu X, Yang SM, Lee TD, Cheff D, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci D, Lukacs CM, Davies DR, Dranow DM, Zhu H, Sulikowski G, Moore WJ, Stott GM, Flint AJ, Hall M, Darley-Usmar VM, Neckers LM, Dang CV, Waterson AG, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , (60), 9184-9204, 2017.

Article Pubmed

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban D, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

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Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.


Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales S, Mott BT, Rai Bantukallu G, Jansen DJ, Henderson M, Urban D, Hall M, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X


Cell Chem Biol , (23), 769-81, 2016.

Article Pubmed

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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation.


Grace PM, Strand KA, Galer EL, Urban D, Wang X, Baratta MV, Fabisiak TJ, Anderson ND, Cheng K, Greene LI, Berkelhammer D, Zhang Y, Ellis AL, Yin HH, Campeau S, Rice KC, Roth BL, Maier SF, Watkins LR


Proc. Natl. Acad. Sci. U.S.A. , (113), E3441-50, 2016.

Article Pubmed

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Cre dependent DREADD (designer receptors exclusively activated by designer drugs) mice.


Zhu H, Aryal DK, Olsen RH, Urban D, Swearingen A, Forbes S, Roth BL, Hochgeschwender U


Genesis , 2016.

Article Pubmed

In Vitro and In Vivo Characterization of the Alkaloid Nuciferine.


Farrell MS, McCorvy JD, Huang XP, Urban D, White KL, Giguere PM, Doak AK, Bernstein AI, Stout KA, Park SM, Rodriguiz RM, Gray BW, Hyatt WS, Norwood AP, Webster KA, Gannon BM, Miller GW, Porter JH, Shoichet BK, Fantegrossi WE, Wetsel WC, Roth BL


PLoS ONE , (11), e0150602, 2016.

Article Pubmed

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Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor.


Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban D, Bass CE, Lichtarge O, Caron MG


Proc. Natl. Acad. Sci. U.S.A. , (112), 7097-102, 2015.

Article Pubmed

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