Program

116
16
6
4
3

Journal Year Published

5
12
5
13
10
12
12
12
7
5
15
10
1

Author

119
183
175
144
135
127
118
115
108
94
87
81
77
57
52
50
45
44
42
34

Category

56
45
28
20
13
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

12
9
6
6
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2

NCATS Publications

Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists.


Patnaik S, Basu D, Southall N, Dehdashti S, Wan K, Zheng W, Ferrer-Alegre M, Taylor M, Engel DA, Marugan JJ


Bioorg. Med. Chem. Lett. , (29), 1113-1119, 2019.

Article Pubmed

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Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.


Fontelonga TM, Jordan B, Nunes AM, Barraza-Flores P, Bolden N, Wuebbles RD, Griner LM, Hu X, Ferrer-Alegre M, Marugan J, Southall N, Burkin DJ


Hum. Mol. Genet. , (28), 2120-2132, 2019.

Article Pubmed

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A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C.


Koh C, Dubey P, Han MAT, Walter PJ, Garraffo HM, Surana P, Southall N, Borochov N, Uprichard SL, Cotler SJ, Etzion O, Heller T, Dahari H, Liang TJ


Antiviral Res. , (163), 149-155, 2019.

Article Pubmed

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A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Advancing precision medicine with personalized drug screening.


Gorshkov K, Chen C, Marshall RE, Mihatov N, Choi Y, Nguyen T, Southall N, Chen KG, Park JK, Zheng W


Drug Discov. Today , 2018.

Article Pubmed

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