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Journal

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NCATS Publications

Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.


Dextras C, Dashnyam M, Griner LAM, Sundaresan J, Chim B, Yu Z, Vodnala S, Lee CR, Hu X, Southall N, Marugan J, Jadhav A, Restifo NP, Acquavella N, Ferrer-Alegre M, Singh A


Sci Rep , (10), 5688, 2020.

Article Pubmed

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Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells.


Singh A, Dashnyam M, Chim B, Escobar TM, Dulcey AE, Hu X, Wilson K, Koganti PP, Spinner CA, Xu X, Jadhav A, Southall N, Marugan J, Selvaraj V, Lazarevic V, Muljo SA, Ferrer-Alegre M


Sci Rep , (10), 3766, 2020.

Article Pubmed

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Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.


Jaynes JM, et al.


Sci Transl Med , (12), 2020.

Article Pubmed

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Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors.


Singh A, Venkannagari S, Oh KH, Zhang Y, Liu L, Rohde JM, Nimmagadda S, Sudini K, Brimacombe K, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, A Mensah G, Wang Z, Ferrer-Alegre M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S


ACS Chem. Biol. , 2016.

Article Pubmed

Tetraspanin CD9 and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties.


Singh A, Lester C, Drapp R, Hu DZ, Glimcher LH, Jones D


Development , (142), 438-43, 2015.

Article Pubmed

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Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.


Singh A, Happel C, Manna SK, Acquaah-Mensah G, Carrerero J, Kumar S, Nasipuri P, Krausz KW, Wakabayashi N, Dewi R, Boros LG, Gonzalez FJ, Gabrielson E, Wong KK, Girnun G, Biswal S


J. Clin. Invest. , (123), 2921-34, 2013.

Article Pubmed

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p27(Kip1) negatively regulates the magnitude and persistence of CD4 T cell memory.


Jatzek A, Tejera MM, Singh A, Sullivan JA, Plisch EH, Suresh M


J. Immunol. , (189), 5119-28, 2012.

Article Pubmed

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.


Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH


J. Clin. Invest. , (122), 91-106, 2012.

Article Pubmed

Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1.


Singh A, Jatzek A, Plisch EH, Srinivasan R, Svaren J, Suresh M


Mol. Cell. Biol. , (30), 5145-59, 2010.

Article Pubmed

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.


Malhotra D, Portales-Casamar E, Singh A, Srivastava S, Arenillas D, Happel C, Shyr C, Wakabayashi N, Kensler TW, Wasserman WW, Biswal S


Nucleic Acids Res. , (38), 5718-34, 2010.

Article Pubmed

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