Program

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Journal Year Published

5
23
16
20
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26
17
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2

Author

183
175
144
135
127
119
118
115
108
94
87
81
77
57
52
50
45
44
42
34

Category

79
74
72
29
15
12
6
1
1

Keyword

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41
35
30
29
24
23
20
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Journal

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NCATS Publications

Thymine DNA glycosylase as a novel target for melanoma.


Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, Testa JR, Davidson G, Davidson I, Larue L, Sobol RW, Yen TJ, Bellacosa A


Oncogene , 2019.

Article Pubmed

Chemically Defined Neural Conversion of Human Pluripotent Stem Cells.


Chen Y, Tristan C, Mallanna SK, Ormanoglu P, Titus S, Simeonov A, Singec I


Methods Mol. Biol. , (1919), 59-72, 2019.

Article Pubmed

Sample image from publication page

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.


Kearney SE, et al.


ACS Cent Sci , (4), 1727-1741, 2018.

Article Pubmed

Sample image from publication page

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).


Sommers JA, Kulikowicz T, Croteau DL, Dexheimer T, Dorjsuren D, Jadhav A, Maloney DJ, Simeonov A, Bohr VA, Brosh RM


PLoS ONE , (14), e0210525, 2019.

Article Pubmed

KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations.


Liu X, Zhang SM, McGeary MK, Krykbaeva I, Lai L, Jansen DJ, Kales S, Simeonov A, Hall M, Kelly DP, Bosenberg MW, Yan Q


Mol. Cancer Ther. , 2018.

Article Pubmed

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.


Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales S, Lal-Nag M, Rai Bantukallu G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K


Cancer Cell , (34), 939-953.e9, 2018.

Article Pubmed

Sample image from publication page

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.


Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page