Program

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Journal Year Published

2
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6
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Author

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182
174
134
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125
118
116
114
108
88
86
81
73
56
51
50
43
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42
34

Category

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5
4
3
1

Keyword

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5
4
3
2
2
2
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Journal

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NCATS Publications

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

Sample image from publication page

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.


Frankowski KJ, et al.


Sci Transl Med , (10), 2018.

Article Pubmed

Sample image from publication page

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.


Al-Ramahi I, Panapakkam Giridharan SS, Chen Y, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer-Alegre M, Southall N, Weisman LS, Botas J, Marugan JJ


Elife , (6), 2017.

Article Pubmed

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Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca(2+) Efflux Channel in the Tubulovesicle.


Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer-Alegre M, Samuelson LC, Merchant JL, Xu H


Dev. Cell , (41), 262-273.e6, 2017.

Article Pubmed

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Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.


Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, Sidransky E, Marugan J, Sue CM, Krainc D


J. Neurosci. , (36), 7693-706, 2016.

Article Pubmed

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A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.


Aflaki E, Borger DK, Moaven N, Stubblefield BK, Rogers SA, Patnaik S, Schoenen FJ, Westbroek W, Zheng W, Sullivan P, Fujiwara H, Sidhu R, Khaliq ZM, Lopez GJ, Goldstein DS, Ory DS, Marugan J, Sidransky E


J. Neurosci. , (36), 7441-52, 2016.

Article Pubmed

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MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.


Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer-Alegre M, Xu H


Nat Commun , (7), 12109, 2016.

Article Pubmed

Sample image from publication page