Program

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Journal Year Published

5
4
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Author

11
182
174
134
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125
118
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114
108
88
86
81
73
56
51
50
43
43
42
34

Category

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5
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Keyword

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1
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Journal

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NCATS Publications

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.


Highland JN, Morris P, Zanos P, Lovett J, Ghosh S, Wang A, Zarate CA, Thomas C, Moaddel R, Gould TD


J. Psychopharmacol. (Oxford) , 269881118812095, 2018.

Article Pubmed

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.


Moaddel R, Shardell M, Khadeer M, Lovett J, Kadriu B, Ravichandran S, Morris P, Yuan P, Thomas C, Gould TD, Ferrucci L, Zarate CA


Psychopharmacology (Berl.) , (235), 3017-3030, 2018.

Article Pubmed

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miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.


Meyer SE, Muench DE, Rogers AM, Newkold TJ, Orr E, O'Brien E, Perentesis JP, Doench JG, Lal A, Morris P, Thomas C, Lieberman J, McGlinn E, Aronow BJ, Salomonis N, Grimes HL


J. Exp. Med. , (215), 2115-2136, 2018.

Article Pubmed

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Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.


Zanos P, Moaddel R, Morris P, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas C, Zarate CA, Gould TD


Pharmacol. Rev. , (70), 621-660, 2018.

Article Pubmed

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Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.


Dyall J, Nelson EA, DeWald LE, Guha R, Hart BJ, Zhou H, Postnikova E, Logue J, Vargas WM, Gross R, Michelotti J, Deiuliis N, Bennett RS, Crozier I, Holbrook MR, Morris P, Klumpp-Thomas C, McKnight C, Mierzwa T, Shinn P, Glass PJ, Johansen LM, Jahrling PB, Hensley LE, Olinger GG, Thomas C, White JM


J. Infect. Dis. , 2018.

Article Pubmed

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Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.


Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris P, Thomas C, Possemato R, Vander Heiden MG, Papagiannakopoulos T


Elife , (6), 2017.

Article Pubmed

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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.


Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau D, Morris P, Zhao J, Thomas C, Monje M


Nature , (549), 533-537, 2017.

Article Pubmed

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Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites.


Morris P, Moaddel R, Zanos P, Moore CE, Gould T, Zarate CA, Thomas C


Org. Lett. , (19), 4572-4575, 2017.

Article Pubmed

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The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.


Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris P, Guha R, Klumpp-Thomas C, McKnight C, Chen Y, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG, White JM


PLoS Negl Trop Dis , (11), e0005540, 2017.

Article Pubmed

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.


Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas C, Zarate CA, Gould TD


Nature , (533), 481-6, 2016.

Article Pubmed

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