Program

85
10
4
1

Journal Year Published

1
3
10
9
18
6
12
7
11
5
3
3

Author

88
185
178
145
136
125
123
118
117
108
99
81
77
58
54
50
46
46
42
37

Category

60
19
19
15
7
2
1
1

Keyword

37
23
16
15
14
12
12
10
7
7
6
6
6
6
5
5
5
5
5
5

Journal

8
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1

NCATS Publications

Quantitative High-Throughput Screening Using an Organotypic Model Identifies Compounds that Inhibit Ovarian Cancer Metastasis.


Kenny HA, Lal-Nag M, Shen M, Kara B, Nahotko DA, Wroblewski K, Fazal S, Chen S, Chiang CY, Chen YJ, Brimacombe K, Marugan J, Ferrer-Alegre M, Lengyel E


Mol. Cancer Ther. , (19), 52-62, 2020.

Article Pubmed

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Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.


Fontelonga TM, Jordan B, Nunes AM, Barraza-Flores P, Bolden N, Wuebbles RD, Griner LM, Hu X, Ferrer-Alegre M, Marugan J, Southall N, Burkin DJ


Hum. Mol. Genet. , (28), 2120-2132, 2019.

Article Pubmed

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A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease.


Vu M, Li R, Baskfield A, Lu B, Farkhondeh Kalat A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, Ory DS, Marugan J, Zheng W


Orphanet J Rare Dis , (13), 152, 2018.

Article Pubmed

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