Program

9
1
1

Journal Year Published

3
2
1
1
1
1

Author

9
185
178
145
136
125
123
118
117
108
99
88
81
77
58
54
50
46
46
42
37

Category

8
5
4
1

Keyword

3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Journal

2
2
1
1
1
1
1

NCATS Publications

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.


Shen M, Asawa R, Zhang Y, Cunningham E, Sun H, Tropsha A, Janzen WP, Muratov EN, Capuzzi SJ, Farag S, Jadhav A, Blatt J, Simeonov A, Martinez N


Oncotarget , (9), 4758-4772, 2018.

Article Pubmed

Sample image from publication page

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban DJ, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

Sample image from publication page

Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease.


Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J


ACS Chem. Biol. , (9), 2594-602, 2014.

Article Pubmed

Sample image from publication page