Program

9
1
1

Journal Year Published

2
3
2
1
1
1
1

Author

11
202
181
149
140
133
133
125
123
108
105
95
82
78
64
63
55
50
46
43
43

Category

8
5
4
1

Keyword

3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Journal

3
2
1
1
1
1
1
1

NCATS Publications

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

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Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.


Shen M, Asawa R, Zhang Y, Cunningham E, Sun H, Tropsha A, Janzen WP, Muratov EN, Capuzzi SJ, Farag S, Jadhav A, Blatt J, Simeonov A, Martinez N


Oncotarget , (9), 4758-4772, 2018.

Article Pubmed

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban DJ, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

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Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease.


Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J


ACS Chem. Biol. , (9), 2594-602, 2014.

Article Pubmed

Sample image from publication page